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SOS1 gene

Known as: SOS1 GUANINE NUCLEOTIDE EXCHANGE FACTOR, Son Of Sevenless Homolog 1 (Drosophila) Gene, HGF 
This gene is involved in guanine nucleotide exchange.
National Institutes of Health

Related topics

Related topics

4 relations
Receptor SignalingSOS2 geneSignal TransductionSon of Sevenless Homolog 1, human

Papers overview

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2015
2015
Differential allelic expression of SOS1 and hyperexpression of the activating SOS1 c.755C variant in a Noonan syndrome family
Noonan syndrome (NS) is a genetic condition characterized by congenital heart defects, short stature and characteristic facial… 
Highly Cited
2010
Highly Cited
2010
The SOS1 transporter of Physcomitrella patens mediates sodium efflux in planta.
• SOS1 is an Na(+)/H(+) antiporter that plays a central role in Na(+) tolerance in land plants. SOS1 mediation of Na(+) efflux… 
2010
2010
Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation
The v-Crk oncogene product consists of two protein interaction modules, a Src homology 2 (SH2) domain and a Src homology 3 (SH3… 
2008
2008
Signaling control of SOS1 mRNA stability
Regulation of mRNA decay rates appears to be an important control point in determining the abundance of gene transcripts. Rapid… 
2007
2007
Cloning of two SOS1 transporters from the seagrass Cymodocea nodosa. SOS1 transporters from Cymodocea and Arabidopsis mediate potassium uptake in bacteria
Two cDNAs isolated from Cymodocea nodosa, CnSOS1A, and CnSOS1B encode proteins with high-sequence similarities to SOS1 plant… 
2002
2002
Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling
A 19 kDa protein was identified to associate with the Dbl oncogene homology domain of Sos1 (Sos–DH) and was purified from rat… 
Highly Cited
2000
Highly Cited
2000
Direct interaction of SOS1 Ras exchange protein with the SH3 domain of phospholipase C-gamma1.
A recent report that microinjection of the SH3 domain of PLC-gamma1 could induce DNA synthesis raised the functional importance… 
Highly Cited
1998
Highly Cited
1998
N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains
ABSTRACT We have studied the functional importance of the N terminus of mouse Sos1 (mSos1), a ubiquitously expressed Ras-specific… 
1997
1997
The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1
We have compared aspects of the mouse sos1 (msos1) and msos2 genes, which encode widely expressed, closely related Ras-specific… 
1995
1995
Structural studies on the PH domains of Db1, Sos1, IRS-1, and beta ARK1 and their differential binding to G beta gamma subunits.
Pleckstrin homology (PH) domains are approximately 110 amino acid residues in length and are structurally conserved in a number… 
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