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SOD2 protein, human

Known as: Mitochondrial Superoxide Dismutase 2, Manangese Superoxide Dismutase, MNSOD 
Superoxide dismutase [Mn], mitochondrial (222 aa, ~25 kDa) is encoded by the human SOD2 gene. This protein plays a role in superoxide reduction.
National Institutes of Health

Related topics

Related topics

12 relations
Cu-Zn Superoxide DismutaseEnzyme GeneErythropoietin Neuroprotection PathwayLongevity Pathway

Broader (2)

Manganese Superoxide Dismutasesuperoxide dismutase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Enhanced drought tolerance of transgenic rice plants expressing a pea manganese superoxide dismutase.
Highly Cited
2004
Highly Cited
2004
p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis
p53-mediated apoptosis may involve the induction of redox-controlling genes, resulting in the production of reactive oxygen… 
Highly Cited
2004
Highly Cited
2004
A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties.
Highly Cited
2004
Highly Cited
2004
Human Endothelial Progenitor Cells Tolerate Oxidative Stress Due to Intrinsically High Expression of Manganese Superoxide Dismutase
Objective—Endothelial progenitor cells (EPCs) display a unique aptitude to promote angiogenesis and restore endothelial function… 
Highly Cited
2003
Highly Cited
2003
SOD2 functions downstream of Sch9 to extend longevity in yeast.
Signal transduction pathways inactivated during periods of starvation are implicated in the regulation of longevity in organisms… 
Highly Cited
1998
Highly Cited
1998
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction
Oxidative stress is implicated in neuronal apoptosis that occurs in physiological settings and in neurodegenerative disorders… 
Highly Cited
1997
Highly Cited
1997
Hydroxyl radical is the major causative factor in stress-induced gastric ulceration.
Highly Cited
1996
Highly Cited
1996
Enhancement of Oxidative Stress Tolerance in Transgenic Tobacco Plants Overproducing Fe-Superoxide Dismutase in Chloroplasts
A chimeric gene consisting of the coding sequence for chloroplastic Fe superoxide dismutase (FeSOD) from Arabidopsis thaliana… 
Review
1993
Review
1993
Cell and tissue responses to oxidative damage.
A broad array of oxidative stresses modulates gene expression in a variety of mammalian cells. One goal of this review was to… 
Highly Cited
1993
Highly Cited
1993
Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin‐1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation
Interleukin‐1 (IL‐1) and tumor necrosis factor (TNF) selectively induce mitochondrial manganese superoxide dismutase (MnSOD… 
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