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Cu-Zn Superoxide Dismutase

Known as: EC 1.15.1.1, Superoxide Dismutase [Cu-Zn], hSod1 
Superoxide dismutase [Cu-Zn] (154 aa, ~16 kDa) is encoded by the human SOD1 gene. This protein is involved in the conversion of superoxides into… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, with astrocytes implicated as contributing substantially to… Expand
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Highly Cited
2010
Highly Cited
2010
Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder characterized by degeneration of… Expand
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Highly Cited
2010
Highly Cited
2010
Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1 (SOD1) that impair motor neuron… Expand
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Highly Cited
2009
Highly Cited
2009
Cytotoxicity induced by silver nanoparticles (AgNPs) and the role that oxidative stress plays in this process were demonstrated… Expand
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Highly Cited
2008
Highly Cited
2008
The antioxidant enzyme superoxide dismutase 1 (SOD1) is a critical player of the antioxidative defense whose activity is altered… Expand
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Highly Cited
2004
Highly Cited
2004
The eukaryotic copper,zinc superoxide dismutases are remarkably stable dimeric proteins that maintain an intrasubunit disulfide… Expand
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Highly Cited
2003
Highly Cited
2003
The most common form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting adult motor neurons, is caused… Expand
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Review
2001
Review
2001
Since its description by Charcot more than 130 years ago, the mechanism underlying the characteristic selective degeneration and… Expand
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Highly Cited
2000
Highly Cited
2000
Cytosolic Cu/Zn superoxide dismutase (SOD1) is a ubiquitous small cytosolic metalloenzyme that catalyzes the conversion of… Expand
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Highly Cited
1995
Highly Cited
1995
Mutation in superoxide dismutase 1 (SOD1), a Cu/Zn enzyme that removes oxygen radicals and protects against oxidative injury, has… Expand
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