Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

SLCO1B1 gene

Known as: solute carrier organic anion transporter family member 1B1, LIVER-SPECIFIC TRANSPORTER 1, OATP-C 
This gene is involved in sodium-independent uptake of numerous endogenous compounds in the liver.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
OBJECTIVES We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. BACKGROUND… Expand
  • figure 1
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND Lowering low-density lipoprotein cholesterol with statin therapy results in substantial reductions in cardiovascular… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
INTRODUCTION Organic anion transporting polypeptide 1B1 (OATP1B1), encoded by the SLCO1B1 gene, mediates the hepatic uptake of… Expand
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Thirty-two healthy volunteers with different SLCO1B1 genotypes ingested a 20 mg dose of atorvastatin and 10 mg dose of… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Background and objective Organic anion transporting polypeptide 1B1 (OATP1B1) is an uptake transporter located at the sinusoidal… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Objectives SLCO1B1*5 and SLCO1B1*15 have been reported to reduce the clearance of pravastatin in healthy volunteers. However… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
This study aimed to characterize possible relationships between polymorphisms in the drug transporter genes organic anion… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Pitavastatin, a novel potent 3-hydroxymethylglutaryl-CoA reductase inhibitor, is selectively distributed to the liver in rats… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
We cloned and expressed a new organic anion transporting polypeptide (OATP), termed human OATP2, (OATP-C, LST-1; symbol SLC21A6… Expand
  • figure 1
  • figure 4
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Based on sequence homology to the human organic anion transporting polypeptide 2 (OATP2; SLC21A6), we cloned a new member of the… Expand
Is this relevant?