SLCO1B1 gene

Known as: solute carrier organic anion transporter family member 1B1, LIVER-SPECIFIC TRANSPORTER 1, OATP-C 
This gene is involved in sodium-independent uptake of numerous endogenous compounds in the liver.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05010019762018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Methotrexate is used to treat autoimmune diseases and malignancies, including acute lymphoblastic leukemia (ALL). Inter… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVES We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. BACKGROUND… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Lowering low-density lipoprotein cholesterol with statin therapy results in substantial reductions in cardiovascular… (More)
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Highly Cited
2007
Highly Cited
2007
Thirty-two healthy volunteers with different SLCO1B1 genotypes ingested a 20 mg dose of atorvastatin and 10 mg dose of… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Organic anion transporting polypeptide 1B1 (OATP1B1, encoded by SLCO1B1 gene) is a hepatic uptake transporter, and its… (More)
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Highly Cited
2001
Highly Cited
2001
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16alpha-carbonitrile (PCN… (More)
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Highly Cited
2001
Highly Cited
2001
Bilirubin, the end product of heme catabolism, is taken up from the blood circulation into the liver. This work identifies a high… (More)
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Highly Cited
1999
Highly Cited
1999
A novel human organic transporter, OATP2, has been identified that transports taurocholic acid, the adrenal androgen… (More)
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Highly Cited
1999
Highly Cited
1999
We have isolated a novel liver-specific organic anion transporter, LST-1, that is expressed exclusively in the human, rat, and… (More)
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Highly Cited
1994
Highly Cited
1994
Using expression cloning in Xenopus laevis oocytes, we have isolated a cDNA encoding a rat liver organic anion-transporting… (More)
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