Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat.

@article{StPierre2004TemporalEP,
  title={Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat.},
  author={Marie V St-Pierre and Thomas Stallmach and A Freimoser Grundschober and J-F Dufour and Mar{\'i}a Angeles Serrano and Jose J G Marin and Yoshiki Sugiyama and Peter J. Meier},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={287 6},
  pages={
          R1505-16
        }
}
Physiological cholestasis linked to immature hepatobiliary transport systems for organic anions occurs in rat and human neonates. In utero, the placenta facilitates vectorial transfer of certain fetal-derived solutes to the maternal circulation for elimination. We compared the ontogenesis of organic anion transporters in the placenta and the fetal liver of the rat to assess their relative abundance throughout gestation and to determine whether the placenta compensates for the late maturation of… CONTINUE READING

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