Skip to search formSkip to main contentSkip to account menu

SLC8A1 gene

Known as: Na+/Ca++ exchanger, SOLUTE CARRIER FAMILY 8 (SODIUM-CALCIUM EXCHANGER), MEMBER 1, Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 1 Gene 
This gene is involved in the modulation of cardiac muscle cell relaxation.
National Institutes of Health

Related topics

Related topics

10 relations
Cardiac Muscle ContractionHomo sapiensIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase.
Phospholemman (PLM) regulates cardiac Na(+)/Ca(2+) exchanger (NCX1) and Na(+)-K(+)-ATPase in cardiac myocytes. PLM, when… 
2006
2006
YM-244769, a Novel Na+/Ca2+ Exchange Inhibitor That Preferentially Inhibits NCX3, Efficiently Protects against Hypoxia/Reoxygenation-Induced SH-SY5Y Neuronal Cell Damage
We investigated the pharmacological properties and interaction domains of N-(3-aminobenzyl)-6-{4-[(3-fluorobenzyl)oxy]phenoxy… 
2005
2005
Phylogeny of Na+/Ca2+ exchanger (NCX) genes from genomic data identifies new gene duplications and a new family member in fish species.
The Na+/Ca2+ exchanger (NCX) is a member of the cation/Ca2+ antiporter (CaCA) family and plays a key role in maintaining cellular… 
Highly Cited
2004
Highly Cited
2004
Plasma Membrane-Cytoskeleton-Endoplasmic Reticulum Complexes in Neurons and Astrocytes*
The possibility that certain integral plasma membrane (PM) proteins involved in Ca2+ homeostasis form junctional units with… 
Highly Cited
2002
Highly Cited
2002
Evidence for cardiac sodium–calcium exchanger association with caveolin‐3
Highly Cited
2002
Highly Cited
2002
The Cardiac Sodium‐Calcium Exchanger Associates with Caveolin‐3
Abstract: The cardiac Na/Ca exchanger's (NCX1) role in calcium homeostasis during myocardial contractility makes it a possible… 
Highly Cited
2002
Highly Cited
2002
The Molecular Determinants of Ionic Regulatory Differences between Brain and Kidney Na+/Ca2+ Exchanger (NCX1) Isoforms*
The Na+/Ca2+exchanger gene NCX1 undergoes alternative splicing leading to several isoforms that differ in a small portion of the… 
2001
2001
A new Na/Ca exchanger splicing pattern identified in situ leads to a functionally active 70kDa NH(2)-terminal protein.
The Na/Ca exchanger (NCX) is an ubiquitous transporter that plays an important role in regulating cellular Ca(2+) balance. On gel… 
1998
1998
Alternative promoters and cardiac muscle cell-specific expression of the Na+/Ca2+exchanger gene.
Many studies have investigated the regulation of the Na+/Ca2+exchanger, NCX1, but limited data exist on transcriptional… 
Highly Cited
1992
Highly Cited
1992
Identification and localization of renal Na(+)-Ca2+ exchanger by polymerase chain reaction.
The molecular identity of the renal Na(+)-Ca2+ exchanger was determined by a homology-based polymerase chain reaction (PCR… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)