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SLC8A1 gene
Known as:
Na+/Ca++ exchanger
, SOLUTE CARRIER FAMILY 8 (SODIUM-CALCIUM EXCHANGER), MEMBER 1
, Solute Carrier Family 8 (Sodium/Calcium Exchanger), Member 1 Gene
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This gene is involved in the modulation of cardiac muscle cell relaxation.
National Institutes of Health
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Related topics
Related topics
10 relations
Cardiac Muscle Contraction
Homo sapiens
Ionophore activity
Ligand Binding
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Engineering Adolescence: Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes
Xiulan Yang
,
Lil Pabon
,
C. Murry
Circulation Research
2014
Corpus ID: 6064176
The discovery of human pluripotent stem cells (hPSCs), including both human embryonic stem cells and human-induced pluripotent…
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Highly Cited
2012
Highly Cited
2012
SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway
R. Kumarswamy
,
A. R. Lyon
,
+9 authors
Thomas Thum
European Heart Journal
2012
Corpus ID: 266906225
Aims Impaired myocardial sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) activity is a hallmark of failing hearts, and SERCA2a…
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Highly Cited
2007
Highly Cited
2007
Cellular and subcellular localization of Na+-Ca2+ exchanger protein isoforms, NCX1, NCX2, and NCX3 in cerebral cortex and hippocampus of adult rat.
A. Minelli
,
P. Castaldo
,
P. Gobbi
,
S. Salucci
,
S. Magi
,
S. Amoroso
Cell Calcium
2007
Corpus ID: 11022099
Highly Cited
2004
Highly Cited
2004
Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle
T. Iwamoto
,
S. Kita
,
+6 authors
T. Katsuragi
Nature Network Boston
2004
Corpus ID: 22603110
Excessive salt intake is a major risk factor for hypertension. Here we identify the role of Na+/Ca2+ exchanger type 1 (NCX1) in…
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Review
1999
Review
1999
Sodium/calcium exchange: its physiological implications.
M. Blaustein
,
W. Jonathan Lederer
Physiological Reviews
1999
Corpus ID: 6963309
The Na+/Ca2+ exchanger, an ion transport protein, is expressed in the plasma membrane (PM) of virtually all animal cells. It…
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Highly Cited
1998
Highly Cited
1998
Differential inhibition of Na+/Ca2+exchanger isoforms by divalent cations and isothiourea derivative.
T. Iwamoto
,
M. Shigekawa
American Journal of Physiology - Cell Physiology
1998
Corpus ID: 4404377
We compared the properties of three mammalian Na+/Ca2+exchanger isoforms, NCX1, NCX2, and NCX3, by analyzing the effects of Ni2…
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Highly Cited
1998
Highly Cited
1998
Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3).
B. Linck
,
Z. Qiu
,
Zhaoping He
,
Q. Tong
,
D. Hilgemann
,
K. Philipson
American Journal of Physiology - Cell Physiology
1998
Corpus ID: 4384863
Three distinct mammalian Na+/Ca2+exchangers have been cloned: NCX1, NCX2, and NCX3. We have undertaken a detailed functional…
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Highly Cited
1997
Highly Cited
1997
Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat.
B. Quednau
,
D. Nicoll
,
K. Philipson
American Journal of Physiology
1997
Corpus ID: 23613946
The gene coding for the Na+/Ca2+ exchanger NCX1 is characterized by a cluster of six exons (A, B, C, D, E, and F) coding for a…
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Highly Cited
1996
Highly Cited
1996
Cloning of a Third Mammalian Na+-Ca2+ Exchanger, NCX3*
D. Nicoll
,
B. Quednau
,
Zhiyong Qui
,
Yu-Rong Xia
,
A. J. Lusis
,
K. Philipson
Journal of Biological Chemistry
1996
Corpus ID: 25125099
NCX3 is the third isoform of a mammalian Na+-Ca2+ exchanger to be cloned. NCX3 was identified from rat brain cDNA by polymerase…
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Highly Cited
1994
Highly Cited
1994
Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger.
Zhaoping Li
,
S. Matsuoka
,
+5 authors
K. Philipson
Journal of Biological Chemistry
1994
Corpus ID: 12213977
The Na(+)-Ca2+ exchanger is an important regulator of cellular Ca2+ levels, and one isoform of this transporter, NCX1, has been…
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