FAQ

SLC7A5 gene

Known as: MEMBRANE PROTEIN E16, CD98, SLC7A5 
This gene plays a role in high-affinity transport of large neutral amino acids.

Topic mentions per year

Topic mentions per year

1980-2017
051019802017

Related topics

Related topics

9 relations
CD98 AntigenHomo sapiensIonophore activityLarge Neutral Amino Acids Transporter Small Subunit 1, human
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
SLC7A5 gene
SLC3A2 gene
Homo sapiens
Transmembrane Transport
Ligand Binding
SLC5A7 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Transport mechanisms of trans-1-amino-3-fluoro[1-(14)C]cyclobutanecarboxylic acid in prostate cancer cells.
INTRODUCTION We investigated the mechanisms of trans-1-amino-3-fluoro[1-(14)C]cyclobutanecarboxylic acid (anti-[(14)C]FACBC… (More)
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2009
2009
System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line.
LAT1, a subunit of heterodimeric system L transporter responsible for transporting neutral amino acids into cells, has been… (More)
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2007
2007
Developmental regulation of nutrient transporter and enzyme mRNA abundance in the small intestine of broilers.
The objective of this study was to investigate intestinal nutrient transporter and enzyme mRNA in broilers selected on corn- and… (More)
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Highly Cited
2006
Highly Cited
2006
L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors.
L-type amino acid transporter 1 (LAT1) is a Na+-independent neutral amino acid transport agency and essential for the transport… (More)
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2004
2004
Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells.
BACKGROUND Spontaneously hypertensive rats (SHR) may have an increased renal production of dopamine. LAT2 promotes L-DOPA renal… (More)
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2001
2001
Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in liver tumor lesions of rat models.
BACKGROUND AND OBJECTIVES It has been said that amino acid transporters play an important role in supplying nutrition to cells… (More)
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2000
2000
Expression of a system L neutral amino acid transporter at the blood-brain barrier.
Amino acid transport system L has been proposed to be one of the major nutrient transport systems at the blood-brain barrier… (More)
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2000
2000
The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.
L-DOPA is transported across the blood-brain barrier (BBB) by an amino acid transporter, system L. Recently, it has been… (More)
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2000
2000
Expression of large amino acid transporter LAT1 in rat brain endothelium.
The expression of the large amino acid transporter, LAT1, was investigated in brain of adult Long-Evans rats. The LAT1 transcript… (More)
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Highly Cited
1998
Highly Cited
1998
Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).
A cDNA was isolated from rat C6 glioma cells by expression cloning which encodes a novel Na+-independent neutral amino acid… (More)
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