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SLC7A5 gene

Known as: MEMBRANE PROTEIN E16, CD98, SLC7A5 
This gene plays a role in high-affinity transport of large neutral amino acids.
National Institutes of Health

Papers overview

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2018
2018
The L-type amino acid transporter 1 (LAT1, SLC7A5) transports essential amino acids across the blood-brain barrier (BBB) and into… Expand
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2014
2014
O-(2-fluoroethyl)-l-tyrosine (FET) labeled with fluorine-18 is an important and specific tracer for diagnostics of glioblastoma… Expand
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2013
2013
Gabapentin is used in the treatment of epilepsy and neuropathic pain. Gabapentin has high and saturable permeability across the… Expand
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2013
2013
The cyanobacterial neurotoxin β-N-methylamino-L-alanine (BMAA) has been implicated in the etiology of neurodegenerative disease… Expand
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2007
2007
We describe a novel strategy to achieve high affinity recognition for the specific, cerebrovascular large neutral amino acid… Expand
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Review
2001
Review
2001
In the last decade, a lot of amino acid transporters were identified by molecular cloning and assigned to the classically… Expand
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2001
2001
In this study, we identify the predominant functional expression of the large, neutral amino acid transporter (LAT1) isoform at… Expand
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2001
2001
Uteroplacental insufficiency causes intrauterine growth restriction (IUGR) and decreases plasma levels of the branched-chain… Expand
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Highly Cited
1999
Highly Cited
1999
Glycoprotein-associated amino acid transporters (gpaAT) are permease-related proteins that require heterodimerization to express… Expand
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Highly Cited
1998
Highly Cited
1998
A cDNA was isolated from rat C6 glioma cells by expression cloning which encodes a novel Na+-independent neutral amino acid… Expand
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