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CD98 Antigen

Known as: CD98, 4F2-antigen, Antigen, CD98 
A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed… 
National Institutes of Health

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Narrower (2)

Antigens, CD98 Heavy ChainSLC3A2 protein, human
In BloodProcess of secretionSLC3A2 geneSLC7A5 gene

Papers overview

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Review
2005
Review
2005
A systematic review of the scientific documentation of fixed partial dentures made from fiber-reinforced polymer to replace missing teeth.
2003
2003
CD98-dependent homotypic aggregation is associated with translocation of protein kinase Cdelta and activation of mitogen-activated protein kinases.
Highly Cited
2001
Highly Cited
2001
Sequence-specific interaction between the disintegrin domain of mouse ADAM 3 and murine eggs: role of beta1 integrin-associated proteins CD9, CD81, and CD98.
ADAM 3 is a sperm surface glycoprotein that has been implicated in sperm-egg adhesion. Because little is known about the adhesive… 
Highly Cited
2000
Highly Cited
2000
TA1/LAT-1/CD98 Light Chain and System L Activity, but Not 4F2/CD98 Heavy Chain, Respond to Arginine Availability in Rat Hepatic Cells
Tumor associated gene-1/L amino acid transporter-1 (TA1/LAT-1) was recently identified as a light chain of the CD98 amino acid… 
2000
2000
Down-Regulation of CD98 in Melphalan-Resistant Myeloma Cells with Reduced Drug Uptake
Although melphalan has been used as a therapeutic reagent for multiple myeloma, many patients become refractory. To elucidate the… 
1998
1998
Pentoxifylline inhibits adhesion and activation of human T lymphocytes.
We have herein studied the effect of pentoxifylline (PTX) on the adhesion and activation of human T lymphocytes. We found that… 
1997
1997
Cross-reactivity of monoclonal antibodies to defined human leucocyte differentiation antigens with bovine cells.
1997
1997
Paramyxovirus-induced syncytium cell formation is suppressed by a dominant negative fusion regulatory protein-1 (FRP-1)/CD98 mutated construct: an important role of FRP-1 in virus-induced cell fusion…
Syncytium formation and subsequent generalized cell fusion have been reported as potentially important mechanisms of virus… 
1997
1997
An anti-fusion regulatory protein-1 monoclonal antibody suppresses human parainfluenza virus type 2-induced cell fusion.
Fusion regulatory protein-1 (FRP-1) regulates virus-mediated cell fusion and induces poly-karyocyte formation of monocytes… 
1987
1987
Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2.
Among the earliest expressed antigens on the surface of activated human lymphocytes is the surface antigen 4F2. We have used DNA… 
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