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SLC22A3 gene

Known as: SOLUTE CARRIER FAMILY 22 (EXTRANEURONAL MONOAMINE TRANSPORTER), MEMBER 3, EXTRANEURONAL MONOAMINE TRANSPORTER, solute carrier family 22 member 3 
This gene is involved in membrane potential-dependent transport of organic cations.
National Institutes of Health

Related topics

Related topics

9 relations
Homo sapiensIonophore activityLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
SLC22A3 is associated with lipoprotein (a) concentration and cardiovascular disease in familial hypercholesterolemia.
2019
2019
“Polytox” synthetic cathinone abuse: A potential role for organic cation transporter 3 in combined cathinone-induced efflux
2018
2018
Mapping of biguanide transporters in human fat cells and their impact on lipolysis
To examine the cell membrane transporters involved in mediating the antilipolytic effect of biguanides in human fat cells. 
2014
2014
Variable allelic expression of imprinted genes in human pluripotent stem cells during differentiation into specialized cell types in vitro.
Highly Cited
2012
Highly Cited
2012
Evaluation of organic cation transporter 3 (SLC22A3) inhibition as a potential mechanism of antidepressant action.
2011
2011
Downregulation of basophil-derived IL-4 and in vivo T(H)2 IgE responses by serotonin and other organic cation transporter 3 ligands.
2010
2010
Interaction of organic cation transporter 3 (SLC22A3) and amphetamine
J. Neurochem. (2010) 114, 142–149. 
2003
2003
Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine.
The aim of this work was to characterize the uptake of 1-methyl-4-phenylpyridinium (MPP(+)) in the JAR human choriocarcinoma cell… 
1998
1998
The extraneuronal monoamine transporter exists in human central nervous system glia.
1996
1996
Disprocynium24, a novel inhibitor of the extraneuronal monoamine transporter, has potent effects on the inactivation of circulating noradrenaline and adrenaline in conscious rat
The role of extraneuronal uptake in terminating the actions of catecholamines has been difficult to evaluate in vivo, largely… 
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