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Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
OBJECTIVE The aim was to formulate clinical practice guidelines for pheochromocytoma and paraganglioma (PPGL). PARTICIPANTS The Task Force included a chair selected by the Endocrine SocietyExpand
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Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans.
Rediscovery of cold-activated brown adipose tissue (BAT) in humans has boosted research interest in identifying BAT activators for metabolic benefits. Of particular interest are cytokines capable ofExpand
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Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health.
CONTEXT Ectopic ACTH secretion (EAS) is difficult to diagnose and treat. We present our experience with EAS from 1983 to 2004. SETTING The study was performed at a tertiary care clinical researchExpand
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Stressor specificity of central neuroendocrine responses: implications for stress-related disorders.
Despite the fact that many research articles have been written about stress and stress-related diseases, no scientifically accepted definition of stress exists. Selye introduced and popularizedExpand
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Recent Advances in Genetics, Diagnosis, Localization, and Treatment of Pheochromocytoma
Dr. Karel Pacak (Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development [NICHD] and Clinical Neurocardiology Section, National Institute ofExpand
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Clinical and molecular genetics of patients with the Carney–Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
Gastrointestinal stromal tumors (GISTs) may be caused by germline mutations of the KIT and platelet-derived growth factor receptor-α (PDGFRA) genes and treated by Imatinib mesylate (STI571) or otherExpand
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Biochemical diagnosis of pheochromocytoma: which test is best?
CONTEXT Diagnosis of pheochromocytoma depends on biochemical evidence of catecholamine production by the tumor. However, the best test to establish the diagnosis has not been determined. OBJECTIVEExpand
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An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis.
BACKGROUND Phaeochromocytomas and paragangliomas are neuro-endocrine tumours that occur sporadically and in several hereditary tumour syndromes, including the phaeochromocytoma-paragangliomaExpand
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Current approaches and recommended algorithm for the diagnostic localization of pheochromocytoma.
  • I. Ilias, K. Pacak
  • Medicine
  • The Journal of clinical endocrinology and…
  • 1 February 2004
Pheochromocytomas (PHEO) (1–3) are catecholamineproducing tumors that arise from chromaffin cells. PHEO are mostly situated within the adrenal medulla, although in about 9–23% of cases, tumorsExpand
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Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
We report a comprehensive molecular characterization of pheochromocytomas and paragangliomas (PCCs/PGLs), a rare tumor type. Multi-platform integration revealed that PCCs/PGLs are driven by diverseExpand
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