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SHR, Rat Strain

Known as: SHR 
SHR: rats develop hypertension spontaneously without exception at the age of 7-15 weeks. There is a systolic blood pressure plateau of about 200 mmHg… Expand
National Institutes of Health

Related topics

Related topics

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Clinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Prognostic factors and prognostic models for renal cell carcinoma: a literature review
PurposeFollowing curative treatment for localised renal cell carcinoma (RCC), up to 30% of patients develop tumour recurrence… Expand
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Highly Cited
2001
Highly Cited
2001
Intercellular movement of the putative transcription factor SHR in root patterning
Positional information is pivotal for establishing developmental patterning in plants, but little is known about the underlying… Expand
Review
2000
Review
2000
Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit/hyperactivity disorder (AD/HD)
  • T. Sagvolden
  • Neuroscience & Biobehavioral Reviews
  • 2000
    • Corpus ID: 23286997
A good model of a disorder is one that: (a) mimics, although in a simpler form than the full-blown clinical case, the… Expand
Highly Cited
2000
Highly Cited
2000
The SHORT-ROOT Gene Controls Radial Patterning of the Arabidopsis Root through Radial Signaling
Asymmetric cell divisions play an important role in the establishment and propagation of the cellular pattern of plant tissues… Expand
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Highly Cited
1999
Highly Cited
1999
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
The human insulin-resistance syndromes, type 2 diabetes, obesity, combined hyperlipidaemia and essential hypertension, are… Expand
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Review
1998
Review
1998
Angiotensin, thirst, and sodium appetite.
Angiotensin (ANG) II is a powerful and phylogenetically widespread stimulus to thirst and sodium appetite. When it is injected… Expand
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Highly Cited
1997
Highly Cited
1997
A multiple-test study of anxiety-related behaviours in six inbred rat strains
Recent studies have underlined the impact of genetic factors in anxiety profiles. In this context, we have initiated a series of… Expand
Highly Cited
1991
Highly Cited
1991
Does superoxide underlie the pathogenesis of hypertension?
Although active oxygen species play important roles in the pathogenesis of various diseases, the molecular mechanism for oxygen… Expand
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Highly Cited
1986
Highly Cited
1986
Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.
To study the mechanism of decreased endothelium-dependent relaxations in spontaneously hypertensive rats (SHR), rings of thoracic… Expand
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Highly Cited
1977
Highly Cited
1977
Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.
The small arteries play an important functional role in establishing the increased peripheral resistance found in essential… Expand
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