Skip to search formSkip to main contentSkip to account menu

SHR, Rat Strain

Known as: SHR 
SHR: rats develop hypertension spontaneously without exception at the age of 7-15 weeks. There is a systolic blood pressure plateau of about 200 mmHg… 
National Institutes of Health

Related topics

Related topics

1 relation
Clinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
Increased nerve growth factor levels in spontaneously hypertensive rats
Objective: Increased sympathetic innervation has been reported in spontaneously hypertensive rats (SHR); however, the precise… 
Highly Cited
1985
Highly Cited
1985
Neuropeptide action in nucleus tractus solitarius: angiotensin specificity and hypertensive rats.
We have reported that microinjection of angiotensin II (ANG II) into the nucleus tractus solitarius of urethan-anesthetized… 
Highly Cited
1985
Highly Cited
1985
Renal and blood pressure responses to synthetic atrial natriuretic factor in spontaneously hypertensive rats.
Atrial natriuretic factor (ANF) is a potent natriuretic and vasorelaxant agent that also stimulates guanosine 3',5'-cyclic… 
Review
1983
Review
1983
Do resistance vessel abnormalities contribute to the elevated blood pressure of spontaneously-hypertensive rats? A review of some of the evidence.
This review summarizes some of the evidence pointing to the existence of vascular abnormalities in the spontaneously hypertensive… 
Highly Cited
1982
Highly Cited
1982
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Prolonged treatment of spontaneously hypertensive (SHR) rats with either methyldopa or clonidine significantly and similarly… 
Highly Cited
1982
Highly Cited
1982
Effect of Lesions of the Anteroventral Third Ventricle (AV3V) on the Development of Hypertension in Spontaneously Hypertensive Rats
Lesions of the anteroventral third ventricle (AV3V), an angiotensin and osmosensitive region of the anterior hypothalamus… 
Highly Cited
1982
Highly Cited
1982
Heparin lowers the blood pressure in hypertensive rats.
This study describes the effect of heparin on blood pressure, cardiac output, and total peripheral resistance in spontaneously… 
Highly Cited
1981
Highly Cited
1981
Analysis of Calcium Handling in Erythrocyte Membranes of Genetically Hypertensive Rats
SUMMARY Calcium handling by erythrocyte membranes was compared in genetically hypertensive (SHR) and normotensive (WKR) rats by… 
Highly Cited
1981
Highly Cited
1981
Hypersensitivity of spontaneously hypertensive rats (SHR) to heat, ether, and immobilization.
The responses to immobilization, ether, and heat of spontaneously hypertensive rats (SHR) and normotensive Sprague-Dawley rats (S… 
1970
1970
Renal vascular resistance in spontaneously hypertensive rats.
The renal vascular beds of one spontaneously hypertensive rat (SHR) and one matched normotensive control rat (NCR) were perfused… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)