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SHR, Rat Strain

Known as: SHR 
SHR: rats develop hypertension spontaneously without exception at the age of 7-15 weeks. There is a systolic blood pressure plateau of about 200 mmHg… 
National Institutes of Health

Papers overview

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Review
1991
Review
1991
Vasoactive hormones acting as endocrine, neuroendocrine, or local hormonal systems (intracrine, autocrine, and paracrine) are an… 
Highly Cited
1988
Highly Cited
1988
We studied the density of the angiotensin II (Ang II) binding site in discrete brain nuclei of 4-week-old and 14-week-old… 
Highly Cited
1987
Highly Cited
1987
The purpose of the present study was to investigate erythrocyte membrane abnormalities in hypertension by means of an electron… 
Highly Cited
1985
Highly Cited
1985
The renal responses to changes in perfusion pressure (RPP) were studied in spontaneously hypertensive rats (SHR) and Wistar-Kyoto… 
Highly Cited
1982
Highly Cited
1982
In metabolic balance studies the intake and excretion of sodium, potassium, and water were measured in spontaneously hypertensive… 
Highly Cited
1982
Highly Cited
1982
Evidence for the brain renin-angiotensin system being involved in the hypertension of the spontaneously hypertensive rat (SHR… 
Highly Cited
1980
Highly Cited
1980
SUMMARY The cardiovascular effects of opioid peptides have been studied. Leudne-enkephalln (Leu- ENK) produced blood pressure (BP… 
Highly Cited
1978
Highly Cited
1978
A chronic, indwelling, tail arterial cannula was implated in conscious undisturbed rats for measurement of blood pressure and… 
Highly Cited
1977
Highly Cited
1977
SUMMARY We investigated vascular reactivity in isolated, Tyrode perfused kidneys from male (blood pressure, 222.6 mm Hg) and… 
Highly Cited
1976
Highly Cited
1976
The possibility that the vascular muscle cell might contribute to the development of essential hypertension by being more…