SHR, Rat Strain

Known as: SHR 
SHR: rats develop hypertension spontaneously without exception at the age of 7-15 weeks. There is a systolic blood pressure plateau of about 200 mmHg… (More)
National Institutes of Health

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Review
2016
Review
2016
Metabolic syndrome (MetS) consists of several medical conditions that collectively predict the risk for cardiovascular disease… (More)
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Highly Cited
2005
Highly Cited
2005
In the spontaneously hypertensive rat (SHR) and aging Wistar-Kyoto rats (WKY), acetylcholine releases an endothelium-derived… (More)
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Highly Cited
2001
Highly Cited
2001
Positional information is pivotal for establishing developmental patterning in plants, but little is known about the underlying… (More)
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Review
2000
Review
2000
A good model of a disorder is one that: (a) mimics, although in a simpler form than the full-blown clinical case, the… (More)
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Highly Cited
2000
Highly Cited
2000
Asymmetric cell divisions play an important role in the establishment and propagation of the cellular pattern of plant tissues… (More)
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Highly Cited
1998
Highly Cited
1998
Superoxide radical (O2-) is increased in the vessel wall of spontaneously hypertensive rats (SHR) where its blockade potentiates… (More)
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Highly Cited
1997
Highly Cited
1997
Recent studies have underlined the impact of genetic factors in anxiety profiles. In this context, we have initiated a series of… (More)
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Highly Cited
1995
Highly Cited
1995
We report the construction of the first complete genetic linkage map of the laboratory rat. By testing 1171 simple sequence… (More)
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Highly Cited
1991
Highly Cited
1991
Although active oxygen species play important roles in the pathogenesis of various diseases, the molecular mechanism for oxygen… (More)
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Highly Cited
1986
Highly Cited
1986
To study the mechanism of decreased endothelium-dependent relaxations in spontaneously hypertensive rats (SHR), rings of thoracic… (More)
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