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Hypoxic Preconditioning Enhances the Benefit of Cardiac Progenitor Cell Therapy for Treatment of Myocardial Infarction by Inducing CXCR4 Expression
Myocardial infarction rapidly depletes the endogenous cardiac progenitor cell pool, and the inefficient recruitment of exogenously administered progenitor cells limits the effectiveness of cardiac… Expand
Functions of angiotensin in the central nervous system.
- M. Phillips
- Annual review of physiology
In this review, the emerging functional roles of the brain angiotensin system have been considered. The major effects of Ang II can be classified into three groups, which imply three possible… Expand
Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction.
BACKGROUND There are several reports that engrafted mesenchymal stem cells (MSCs) stimulate angiogenesis in the ischemic heart, but the mechanism remains controversial. We hypothesize that… Expand
Levels of angiotensin and molecular biology of the tissue renin angiotensin systems
The cloning of renin, angiotensinogen and angiotensin converting enzyme genes have established a widespread presence of these components of the renin-angiotensin system in multiple tissues. New sites… Expand
Angiotensin II in central nervous system physiology
In summary, the prevailing concept is that brain Ang II increases blood pressure by activating AT1 receptors, and that these have a neuromodulating effect to increase the activity of autonomic… Expand
Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector.
- Y. Tang, Y. Tang, Y. Zhang, K. Qian, L. Shen, M. Phillips
- Journal of the American College of Cardiology
- 4 October 2005
OBJECTIVES The goal of this study was to modify mesenchymal stem cells (MSCs) cells with a hypoxia-regulated heme oxygenase-1 (HO-1) plasmid to enhance the survival of MSCs in acute myocardial… Expand
The multiple actions of angiotensin II in atherosclerosis
Angiotensin II (Ang II), the effector peptide of the renin-angiotensin system, has been implied in the pathogenesis of atherosclerosis on various levels. There is abundant experimental evidence that… Expand
MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats.
- U. P. R. Soci, T. Fernandes, +6 authors E. M. Oliveira
- Biology, Medicine
- Physiological genomics
- 1 June 2011
MiRNAs regulate cardiac development, hypertrophy, and angiogenesis, but their role in cardiac hypertrophy (CH) induced by aerobic training has not previously been studied. Aerobic training promotes… Expand
The effect of ouabain on water diffusion in the rat hippocampal slice measured by high resolution NMR imaging
- D. Buckley, J. Bui, +4 authors S. Blackband
- Chemistry, Medicine
- Magnetic resonance in medicine
- 1 January 1999
High resolution NMR imaging of the isolated perfused rat hippocampal slice was used to quantitate ADC changes following ouabain‐induced cell swelling. Hippocampal slices were studied in artificial… Expand
Effect of exercise training on blood pressure in 70- to 79-yr-old men and women.
- C. Cononie, J. E. Graves, M. Pollock, M. Phillips, C. Sumners, J. Hagberg
- Medicine and science in sports and exercise
- 1 April 1991
Men and women 70-79 yr of age (N = 49) were studied to assess the effect of 6 months of resistance or endurance exercise training on their blood pressure, hemodynamic parameters, and pressor hormone… Expand