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SETDB1 protein, human

Known as: Histone-Lysine N-Methyltransferase SETDB1, SET Domain Bifurcated 1, Lysine N-Methyltransferase 1E 
Histone-lysine N-methyltransferase SETDB1 (1291 aa, ~143 kDa) is encoded by the human SETDB1 gene. This protein is involved in histone methylation.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The most common mutation in human melanoma, BRAF(V600E), activates the serine/threonine kinase BRAF and causes excessive activity… 
Highly Cited
2010
Highly Cited
2010
Endogenous retroviruses (ERVs), retrovirus-like elements with long terminal repeats, are widely dispersed in the euchromatic… 
Review
2010
Review
2010
More than forty per cent of the mammalian genome is derived from retroelements, of which about one-quarter are endogenous… 
Review
2009
Review
2009
Osteoblasts and adipocytes differentiate from a common pluripotent precursor, the mesenchymal stem cell (MSC). Studies have… 
Highly Cited
2009
Highly Cited
2009
Transcription factors that play key roles in regulating embryonic stem (ES) cell state have been identified, but the chromatin… 
Highly Cited
2006
Highly Cited
2006
DNA CpG methylation can cooperate with histone H3 lysine 9 (H3-K9) methylation in heterochromatin formation and gene silencing… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT KAP1/TIF1β is proposed to be a universal corepressor protein for the KRAB zinc finger protein (KRAB-zfp) superfamily of… 
Highly Cited
2002
Highly Cited
2002
Posttranslational modification of histones has emerged as a key regulatory signal in eukaryotic gene expression. Recent genetic…