FAQ

SAP kinase activity

Known as: SAPK, stress-activated kinase activity, stress-activated protein kinase activity 
Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2008
02419952008

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1 relation
SAPK

Related mentions per year

Related mentions per year

1995-2016
1990200020102020
SAP kinase activity
SAPK

Papers overview

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2001
2001
Inhibition of stress-activated protein kinase in the ischemic/reperfused heart: role of magnesium tanshinoate B in preventing apoptosis.
The activation of stress-activated protein (SAP) kinase may lead to an induction of apoptosis that is responsible for part of the… (More)
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2000
2000
Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.
The cellular response to DNA damage includes activation of the nuclear Lyn protein tyrosine kinase. Using cells deficient in Lyn… (More)
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2000
2000
P2Y receptor-mediated inhibition of tumor necrosis factor alpha -stimulated stress-activated protein kinase activity in EAhy926 endothelial cells.
In the EAhy926 endothelial cell line, UTP, ATP, and forskolin, but not UDP and epidermal growth factor, inhibited tumor necrosis… (More)
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Highly Cited
1999
Highly Cited
1999
c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms.
c-Jun is a component of the transcription factor AP-1, which is activated by a wide variety of extracellular stimuli. The… (More)
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1998
1998
Regulation of Bcr-Abl-induced SAP kinase activity and transformation by the SHPTP1 protein tyrosine phosphatase
The oncogenic Bcr-Abl variant of the c-Abl tyrosine kinase transforms cells by a mechanism dependent on activation of the stress… (More)
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1997
1997
Nitric oxide modulates the c-Jun N-terminal kinase/stress-activated protein kinase activity through activating c-Jun N-terminal kinase kinase.
Nitric oxide is a signaling molecule that has a broad range of physiological functions, including neurotransmission, macrophage… (More)
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1995
1995
Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation.
The activity of stress-activated protein (SAP) kinase is stimulated by diverse agents such as tumor necrosis factor, UV light… (More)
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1995
1995
c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine.
Previous work has shown that treatment of cells with the antimetabolite 1-beta-D-arabinofuranosylcytosine (ara-C) is associated… (More)
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1995
1995
Involvement of stress-activated protein kinase in the cellular response to 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents.
The cellular response to 1-beta-D-arabinofuranosylcytosine (ara-C) includes activation of Jun/AP-1, induction of c-jun… (More)
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1995
1995
Ionizing radiation stimulates a Grb2-mediated association of the stress-activated protein kinase with phosphatidylinositol 3-kinase.
The stress-activated protein (SAP) kinases are induced by tumor necrosis factor, oncoproteins, and UV light. The present studies… (More)
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