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S1PR3 wt Allele

Known as: S1P3, Sphingosine-1-Phosphate Receptor 3 wt Allele, LPB3 
Human S1PR3 wild-type allele is located within 9q22.1-q22.2 and is approximately 14 kb in length. This allele, which encodes sphingosine 1-phosphate… 
National Institutes of Health

Related topics

Related topics

8 relations
G Protein-Coupled Receptor SignalingLigand BindingPhospholipid BindingReceptor Signaling

Broader (1)

S1PR3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
ETS-1-mediated Transcriptional Up-regulation of CD44 Is Required for Sphingosine-1-phosphate Receptor Subtype 3-stimulated Chemotaxis*
Background: S1P3-mediated chemotaxis plays a pivotal role in various physiological and pathophysiological activities. Results… 
2008
2008
Interactions between sphingosine-1-phosphate and vascular endothelial growth factor signalling in ML-1 follicular thyroid carcinoma cells.
Sphingosine-1-phosphate (S1P) induces migration of human ML-1 thyroid follicular cancer cells and inhibits migration of human FRO… 
2007
2007
Identification of Leu276 of the S1P1 Receptor and Phe263 of the S1P3 Receptor in Interaction with Receptor Specific Agonists by Molecular Modeling, Site-Directed Mutagenesis, and Affinity Studies
Sphingosine-1-phosphate (S1P) receptor agonists are novel immunosuppressive agents. The selectivity of S1P1 against S1P3 is… 
2006
2006
BML‐241 fails to display selective antagonism at the sphingosine‐1‐phosphate receptor, S1P3
The thiazolidine carboxylic acid, BML‐241, has been proposed as a lead compound in development of selective antagonists at the… 
Highly Cited
2003
Highly Cited
2003
Sphingosine 1-Phosphate in Amniotic Fluid Modulates Cyclooxygenase-2 Expression in Human Amnion-derived WISH Cells*
The metabolism of arachidonic acid, in particular the generation of prostaglandins (PGs), has been proposed to play a key role in… 
Highly Cited
2003
Highly Cited
2003
High density lipoprotein-associated lysosphingolipids reduce E-selectin expression in human endothelial cells.
Highly Cited
2002
Highly Cited
2002
Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships.
Sphingosine-1-phosphate (S1P) is an intracellular second messenger and an extracellular mediator through endothelial… 
Highly Cited
2001
Highly Cited
2001
Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins.
Sphingosine 1-phosphate (SPP), a platelet-derived bioactive lysophospholipid, is a regulator of angiogenesis. However, molecular… 
Review
2000
Review
2000
Sphingosine‐1‐Phosphate Signaling via the EDG‐1 Family of G‐Protein‐Coupled Receptors
Abstract: The bioactive lipid sphingosine‐1‐phosphate (SPP) is abundantly formed and released during the activation of platelets… 
2000
2000
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells.
Sphingosine 1-phosphate (S-1-P), a lipid mediator shown to be a ligand for aortic G protein-coupled receptor [corrected] (AGRs… 
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