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S1PR2 wt Allele

Known as: EDG-5, EDG5, H218 
Human S1PR2 wild-type allele is located in the vicinity of 19p13.2 and is approximately 10 kb in length. This allele, which encodes sphingosine 1… 
National Institutes of Health

Related topics

Related topics

9 relations
19p13.2Cytoskeletal ModelingG Protein-Coupled Receptor SignalingLigand Binding

Broader (1)

S1PR2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Sphingolipids inhibit vimentin-dependent cell migration
ABSTRACT The sphingolipids, sphingosine 1-phosphate (S1P) and sphingosylphosphorylcholine (SPC), can induce or inhibit cellular… 
2009
2009
The S1P2 receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes
Sphingosine-1-phosphate (S1P) is known to affect platelet responsiveness but the receptor mediating these effects and the… 
2008
2008
Sphingosine‐1‐phosphate acts as a developmental stage specific inhibitor of platelet‐derived growth factor‐induced chemotaxis of osteoblasts
The development and maintenance of a healthy skeleton depends on the migration of cells to areas of new bone formation… 
Highly Cited
2006
Highly Cited
2006
Negative regulation of endothelial morphogenesis and angiogenesis by S1P2 receptor.
Highly Cited
2003
Highly Cited
2003
Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor
Highly Cited
2002
Highly Cited
2002
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist.
Review
2002
Review
2002
Lysophospholipid Receptors in the Nervous System
The lysophospholipid mediators, lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P), are responsible for cell signaling… 
Review
2000
Review
2000
Sphingosine‐1‐Phosphate Signaling via the EDG‐1 Family of G‐Protein‐Coupled Receptors
Abstract: The bioactive lipid sphingosine‐1‐phosphate (SPP) is abundantly formed and released during the activation of platelets… 
2000
2000
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells.
Sphingosine 1-phosphate (S-1-P), a lipid mediator shown to be a ligand for aortic G protein-coupled receptor [corrected] (AGRs… 
1997
1997
Embryonic expression pattern of H218, a G-protein coupled receptor homolog, suggests roles in early mammalian nervous system development
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