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S1PR2 gene

Known as: S1P2, ENDOTHELIAL DIFFERENTIATION GENE 5, Sphingosine-1-Phosphate Receptor 2 Gene 
This gene is involved in both cell proliferation and cell survival.
National Institutes of Health

Related topics

Related topics

10 relations
Cytoskeletal ModelingG Protein-Coupled Receptor SignalingLigand BindingPhospholipid Binding

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S1PR2 wt Allele

Papers overview

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2016
2016
Transforming growth factor-β-sphingosine kinase 1/S1P signaling upregulates microRNA-21 to promote fibrosis in renal tubular epithelial cells
Renal fibrosis is a progressive pathological change characterized by tubular cell apoptosis, tubulointerstitial fibroblast… 
2015
2015
Sphingolipids inhibit vimentin-dependent cell migration
ABSTRACT The sphingolipids, sphingosine 1-phosphate (S1P) and sphingosylphosphorylcholine (SPC), can induce or inhibit cellular… 
2013
2013
Epidermal growth factor‐induced cellular invasion requires sphingosine‐1‐phosphate/sphingosine‐1‐phosphate 2 receptor‐mediated ezrin activation
Ezrin, radixin, and moesin (ERM) proteins link cortical actin to the plasma membrane and coordinate cellular events that require… 
2013
2013
Interrogation of sphingosine-1-phosphate receptor 2 function in vivo reveals a prominent role in the recovery from IgE and IgG-mediated anaphylaxis with minimal effect on its onset.
2012
2012
Knockdown of the sphingosine-1-phosphate receptor S1PR1reduces pain behaviors induced by local inflammation of the rat sensory ganglion
Highly Cited
2010
Highly Cited
2010
Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells.
2010
2010
Downregulation of sphingosine-1-phosphate receptors in bronchial smooth muscle of mouse experimental asthma.
2001
2001
Genomic analysis of a mouse model of immunoglobulin A nephropathy reveals an enhanced PDGF–EDG5 cascade
The molecular mechanism of immunoglobulin A nephropathy (IgAN), the most common primary renal glomerular disease worldwide, is… 
2000
2000
Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells.
Sphingosine 1-phosphate (S-1-P), a lipid mediator shown to be a ligand for aortic G protein-coupled receptor [corrected] (AGRs… 
2000
2000
Antisense Studies in PC12 Cells Suggest a Role for H218, a Sphingosine 1-Phosphate Receptor, in Growth-Factor-Induced Cell-Cell Interaction and Neurite Outgrowth
Our previous studies of H218, a sphingosine 1-phosphate (S1P) receptor and a member of the G-protein-coupled receptor superfamily… 
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