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Retinoic Acid Receptor

Known as: Retinoic Acid Receptors, Nuclear Receptor Subfamily 1 Group B, Receptors, Retinoic Acid [Chemical/Ingredient] 
Proteins in the nucleus or cytoplasm that specifically bind RETINOIC ACID or RETINOL and trigger changes in the behavior of cells. Retinoic acid… 
National Institutes of Health

Related topics

Related topics

42 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Narrower (6)

RARB2 protein, humanRARRES3 protein, humanretinoic acid binding protein I, cellularretinoic acid binding protein II, cellular

Papers overview

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Highly Cited
1998
Highly Cited
1998
Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia
The transforming proteins of acute promyelocytic leukaemias (APL) are fusions of the promyelocytic leukaemia (PML) and the… 
Review
1996
Review
1996
A decade of molecular biology of retinoic acid receptors
  • P. Chambon
  • FASEB journal : official publication of the…
  • 1996
  • Corpus ID: 23723843
Retinoids play an important role in development, differentiation, and homeostasis. The discovery of retinoid receptors belonging… 
Highly Cited
1995
Highly Cited
1995
Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid
The 2.0-Å crystal structure of the ligand-binding domain (LBD) of the human retinoic acid receptor (RAR)-γ bound to all-trans… 
Highly Cited
1992
Highly Cited
1992
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
CELLULAR responsiveness to retinoic acid and its metabolites is conferred through two structurally and pharmacologically… 
Highly Cited
1992
Highly Cited
1992
9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα
VITAMIN A (retinol) and its natural derivatives are required for many physiological processes1–3. The activity of retinoids is… 
Highly Cited
1992
Highly Cited
1992
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.
An understanding of the differences and similarities of the retinoid X receptor (RXR) and retinoic acid receptor (RAR) systems… 
Highly Cited
1991
Highly Cited
1991
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid).
BACKGROUND AND METHODS Patients with acute promyelocytic leukemia have a characteristic (15;17) translocation, with a breakpoint… 
Highly Cited
1990
Highly Cited
1990
Nuclear receptor that identifies a novel retinoic acid response pathway
Molecular cloning and transcriptional activation studies have revealed a new protein similar to the steroid hormone receptors and… 
Highly Cited
1990
Highly Cited
1990
The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus
RETINOIC acid is a vitamin A derivative with striking effects on development and cell differentiation1–3. Several nuclear… 
Review
1987
Review
1987
A human retinoic acid receptor which belongs to the family of nuclear receptors
A cDNA encoding a protein that binds retinoic acid with high affinity has been cloned. The protein is homologous to the receptors… 
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