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Recombinant Interferon Beta

Known as: Beta Interferon, Interferon Beta, Interferon-beta 
A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous… 
National Institutes of Health

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BetaseronFeronRebif
Cytokine Receptor ActivationGene Expression RegulationInhibition of Cell ProliferationInterferon-beta

Papers overview

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Highly Cited
2007
Highly Cited
2007
Long-Term Adherence to Interferon β Therapy in Relapsing-Remitting Multiple Sclerosis
Background/Aims: To assess the proportion and the reasons of drop-outs in relapsing-remitting multiple sclerosis patients treated… 
Highly Cited
2003
Highly Cited
2003
Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro.
Highly Cited
2001
Highly Cited
2001
Molecular Cross-talk between the TRAIL and Interferon Signaling Pathways *
TRAIL/APO-2L induces apoptosis in a variety of transformed cells and has potential as an anti-cancer therapeutic. The physiologic… 
Highly Cited
2001
Highly Cited
2001
Human monocyte-derived dendritic cells produce bioactive gelatinase B: inhibition by IFN-beta.
We studied the secretion of gelatinase B by dendritic cells (DC) generated by culturing human peripheral blood monocytes in… 
Highly Cited
2001
Highly Cited
2001
Intact nitric oxide synthase II gene is required for interferon-beta-mediated suppression of growth and metastasis of pancreatic adenocarcinoma.
Previous studies have shown that enforced expression of IFN-beta suppressed tumor growth and metastasis. In this report, we… 
Highly Cited
1994
Highly Cited
1994
Interferon-beta endogenously produced by intratumoral injection of cationic liposome-encapsulated gene: cytocidal effect on glioma transplanted into nude mouse brain.
The cytocidal effect of endogenously produced human interferon-beta was tested on glioma transplanted into the brain of nude mice… 
Highly Cited
1993
Highly Cited
1993
In vitro and in vivo inhibition of mitogen‐driven T‐cell activation by recombinant interferon beta
Recombinant interferon beta (rIFNβ) is being tested as experimental immunotherapy for exacer-bating-remitting MS. To clarify the… 
1989
1989
HIV replication can be blocked by recombinant human interferon beta.
Recombinant human interferon beta (rIFN-beta) reduces replication of HIV in cultured peripheral mononuclear cells. The effect is… 
Highly Cited
1988
Highly Cited
1988
Murine hybridoma/plasmacytoma growth factor. Complete amino-acid sequence and relation to human interleukin-6.
Murine interleukin-HP1 (HP1) was originally identified as a T-cell-derived lymphokine with growth factor activity for B-cell… 
Highly Cited
1983
Highly Cited
1983
Structure and expression of a cloned cDNA for mouse interferon-beta.
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