Recombinant Interferon Beta

Known as: Beta Interferon, Interferon Beta, Interferon-beta 
A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The effect of interferon-beta in multiple sclerosis is modest and many patients do not respond to treatment. To date, no single… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Oncolytic viruses hold much promise for clinical treatment of many cancers, but a lack of systemic delivery and… (More)
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Highly Cited
2007
Highly Cited
2007
Autophagy has recently been shown to be an important component of the innate immune response. The signaling pathways leading to… (More)
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Highly Cited
2007
Highly Cited
2007
Transcriptional activation of the interferon-beta (IFN-beta) gene requires assembly of an enhanceosome containing ATF-2/c-Jun… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Neutralizing antibodies (NABs) occur frequently in patients receiving interferon (IFN)-beta for multiple sclerosis (MS… (More)
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Highly Cited
2005
Highly Cited
2005
Viral infection triggers host innate immune responses through activation of the transcription factors NF-kappaB and IRF 3, which… (More)
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Highly Cited
2005
Highly Cited
2005
Rhinoviruses are the major trigger of acute asthma exacerbations and asthmatic subjects are more susceptible to these infections… (More)
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Highly Cited
2003
Highly Cited
2003
Type I interferons (IFN-alpha/beta) affect many aspects of immune responses. Many pathogen-associated molecules, including… (More)
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Highly Cited
1998
Highly Cited
1998
We have identified a virus-activated factor (VAF) that binds to a regulatory element shared by different virus-inducible genes… (More)
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Highly Cited
1997
Highly Cited
1997
A functional interferon-beta gene enhanceosome was assembled in vitro using the purified recombinant transcriptional activator… (More)
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