Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
It is demonstrated that in mammalian cells, the transcription coactivator YAP (Yes-associated protein), is inhibited by cell density via the Hippo pathway, and YAP overexpression regulates gene expression in a manner opposite to cell density, and is able to overcome cell contact inhibition.
TEAD mediates YAP-dependent gene induction and growth control.
TEAD is revealed as a new component in the Hippo pathway playing essential roles in mediating biological functions of YAP, and is required for YAP-induced cell growth, oncogenic transformation, and epithelial-mesenchymal transition.
The Mutational Landscape of Lethal Castrate Resistant Prostate Cancer
The mutational landscape of a heavily treated metastatic cancer is described, novel mechanisms of AR signalling deregulated in prostate cancer are identified, and candidates for future study are prioritize.
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
Development of human protein reference database as an initial platform for approaching systems biology in humans.
This unified bioinformatics platform will be useful in cataloging and mining the large number of proteomic interactions and alterations that will be discovered in the postgenomic era.
The polycomb group protein EZH2 is involved in progression of prostate cancer
Dysregulated expression of EZH2 may be involved in the progression of prostate cancer, as well as being a marker that distinguishes indolent prostate cancer from those at risk of lethal progression.
ONCOMINE: a cancer microarray database and integrated data-mining platform.
Integrative Clinical Genomics of Advanced Prostate Cancer