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Receptors, Progesterone

Known as: Receptors, Progesterone [Chemical/Ingredient], pr, Progesterone Receptors 
Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor… 
National Institutes of Health

Related topics

Related topics

19 relations
In BloodMifepristonePGR genePGR wt Allele

Narrower (5)

PGRMC1 protein, humanProgesterone Receptor, humanpr2 protein, Xenopusprogesterone receptor A

Broader (2)

Proteinssteroid hormone receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Progesterone receptor modulates estrogen receptor-α action in breast cancer
Progesterone receptor (PR) expression is used as a biomarker of oestrogen receptor-α (ERα) function and breast cancer prognosis… 
Highly Cited
2013
Highly Cited
2013
Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer.
PURPOSE Current immunohistochemical (IHC)-based definitions of luminal A and B breast cancers are imperfect when compared with… 
Highly Cited
2012
Highly Cited
2012
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. We sequenced and analyzed the whole… 
Highly Cited
2005
Highly Cited
2005
Immunohistochemistry of estrogen and progesterone receptors reconsidered: experience with 5,993 breast cancers.
Paraffin sections or fine-needle aspiration smears from 5,993 cases of invasive mammary carcinomas were assessed… 
Highly Cited
2003
Highly Cited
2003
Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases.
PURPOSE To determine whether progesterone receptor (PgR) status provides additional value to estrogen receptor (ER) status and… 
Review
2002
Review
2002
Reproductive functions of progesterone receptors.
The steroid hormone progesterone plays a central role in the reproductive events associated with pregnancy establishment and… 
Highly Cited
2000
Highly Cited
2000
Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome.
Ligand-dependent down-regulation that leads to rapid and extensive loss of protein is characteristic of several nuclear steroid… 
Highly Cited
1998
Highly Cited
1998
A paracrine role for the epithelial progesterone receptor in mammary gland development.
Recently generated progesterone receptor (PR)-negative (PR-/-) mice provide an excellent model for dissecting the role of… 
Highly Cited
1980
Highly Cited
1980
The value of estrogen and progesterone receptors in the treatment of breast cancer
The estrogen receptor (ER) assay has become a standard practice in the management of advanced breast cancer. Tumors lacking ER… 
Highly Cited
1978
Highly Cited
1978
Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen.
Estrogen antagonists are widely used in the treatment of breast cancer, and studies of their mechanism of action may provide… 
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