FAQ

Mifepristone

Known as: (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one, Mifepristone [Chemical/Ingredient], Mifepristonum 
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
05010015019552017

Related topics

Related topics

35 relations
Abortifacient AgentsAdnexal DiseasesAdrenal Cortex DiseasesBrain Neoplasms
(More)

Broader (6)

Contraceptive Agents, FemaleContraceptives, Postcoital, SyntheticEstranesHormone Antagonists
(More)

Narrower (10)

MifegyneMifeprexR-38486RU 40555
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Mifepristone
Drug Allergy
Brain Neoplasms
In Blood
Receptors, Progesterone
Adrenal Cortex Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome.
CONTEXT Cushing's syndrome (CS) is a disorder associated with significant morbidity and mortality due to prolonged exposure to… (More)
  • table 1
  • table 2
  • figure 2
  • table 3
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress.
In rodents, stress suppresses adult neurogenesis. This is thought to involve activation of glucocorticoid receptors in the brain… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis.
The glucocorticoid receptor antagonist mifepristone has been shown to rapidly and effectively ameliorate symptoms of psychotic… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Improvements in Neurocognitive Function and Mood Following Adjunctive Treatment with Mifepristone (RU-486) in Bipolar Disorder
High cortisol levels are found in severe mood disorders, particularly bipolar disorder. Hypercortisolaemia may cause or… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial.
BACKGROUND A single 10 mg dose of mifepristone, and two 0.75 mg doses of levonorgestrel 12 h apart, are effective for emergency… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
An open label trial of C-1073 (mifepristone) for psychotic major depression.
BACKGROUND The rationale for treating patients with psychotic major depression (PMD) with glucocorticosteroid receptor (GR… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
A conditional tissue-specific transgene expression system using inducible GAL4.
In Drosophila, the most widely used system for generating spatially restricted transgene expression is based on the yeast GAL4… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Early pregnancy termination with mifepristone and misoprostol in the United States.
BACKGROUND Mifepristone and a prostaglandin have been used successfully to terminate pregnancy in Europe and China. We report the… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Induction of abortion with mifepristone (RU 486) and oral or vaginal misoprostol.
BACKGROUND Medical termination of pregnancy can be successfully performed with a combination of mifepristone (RU 486) and a… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Treatment of unresectable meningiomas with the antiprogesterone agent mifepristone.
The possibility that meningioma growth may be related to female sex hormone levels is suggested by several lines of evidence… (More)
Is this relevant?