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Mifepristone

Known as: (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one, Mifepristone [Chemical/Ingredient], Mifepristonum 
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early… 
National Institutes of Health

Related topics

Related topics

38 relations
Abortifacient AgentsAdnexal DiseasesAdrenal Cortex DiseasesBrain Neoplasms

Broader (7)

Abortifacient Agents, SteroidalContraceptive Agents, FemaleContraceptives, Postcoital, SyntheticEstranes

Narrower (12)

MifegyneMifeprexR-38486RU 40555

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Requests for Abortion in Latin America Related to Concern about Zika Virus Exposure.
With the rapid emergence of Zika virus throughout Latin America and its association with microcephaly, requests for access to… 
Highly Cited
2005
Highly Cited
2005
Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages
Highly Cited
2005
Highly Cited
2005
Acute stress suppresses pro-inflammatory cytokines TNF-α and IL-1β independent of a catecholamine-driven increase in IL-10 production
Highly Cited
2004
Highly Cited
2004
Acceptability of home-use of misoprostol in medical abortion.
Highly Cited
2004
Highly Cited
2004
Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
Review
2003
Review
2003
Pharmacologic properties of CDB(VA)-2914
Highly Cited
2001
Highly Cited
2001
Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: implications for mood disorders
Review
2000
Review
2000
Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer
Highly Cited
1997
Highly Cited
1997
Clinical Pharmacokinetics of Mifepristone
SummaryMifepristone is a steroidal antiprogestin and antiglucocorticoid acting at the receptor level. The aromatic… 
Highly Cited
1995
Highly Cited
1995
Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures
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