Mifepristone

Known as: (aa Beta, 17 beta)-11-[4-(dimethylamino)-phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one, Mifepristone [Chemical/Ingredient], Mifepristonum 
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1955-2018
05010015019552017

Papers overview

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Highly Cited
2012
Highly Cited
2012
CONTEXT Cushing's syndrome (CS) is a disorder associated with significant morbidity and mortality due to prolonged exposure to… (More)
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Highly Cited
2007
Highly Cited
2007
In rodents, stress suppresses adult neurogenesis. This is thought to involve activation of glucocorticoid receptors in the brain… (More)
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Highly Cited
2006
Highly Cited
2006
The glucocorticoid receptor antagonist mifepristone has been shown to rapidly and effectively ameliorate symptoms of psychotic… (More)
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Highly Cited
2004
Highly Cited
2004
High cortisol levels are found in severe mood disorders, particularly bipolar disorder. Hypercortisolaemia may cause or… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND A single 10 mg dose of mifepristone, and two 0.75 mg doses of levonorgestrel 12 h apart, are effective for emergency… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The rationale for treating patients with psychotic major depression (PMD) with glucocorticosteroid receptor (GR… (More)
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Highly Cited
2001
Highly Cited
2001
In Drosophila, the most widely used system for generating spatially restricted transgene expression is based on the yeast GAL4… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Mifepristone and a prostaglandin have been used successfully to terminate pregnancy in Europe and China. We report the… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Medical termination of pregnancy can be successfully performed with a combination of mifepristone (RU 486) and a… (More)
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Highly Cited
1991
Highly Cited
1991
The possibility that meningioma growth may be related to female sex hormone levels is suggested by several lines of evidence… (More)
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