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Endocrine regulation of menstruation.
In women, endometrial morphology and function undergo characteristic changes every menstrual cycle. These changes are crucial for perpetuation of the species and are orchestrated to prepare the… Expand
Cytokine control in human endometrium.
Cytokines within endometrium participate in both menstruation and implantation but also contribute to the defence mechanisms of the mucosal epithelium. Endometrium is under the control of steroid… Expand
The endocrinology of menstruation – a role for the immune system
The human endometrium displays characteristic features, both structural and functional, across the menstrual cycle. It is the sex steroid hormones, oestrogen and progesterone, that drive the… Expand
Chemokine and cyclooxygenase-2 expression in human endometrium coincides with leukocyte accumulation.
The endometrium contains a resident population of leukocytes, the number and subtype of which vary throughout the menstrual cycle and in early pregnancy. Factors controlling these fluctuations are… Expand
Changes in urinary cytokines and soluble intercellular adhesion molecule‐1 (ICAM‐1) in bladder cancer patients after Bacillus Calmette—Guérin (BCG) immunotherapy
- A. Jackson, A. Alexandroff, +5 authors K. James
- Clinical and experimental immunology
- 1 March 1995
Intravesical immunotherapy for carcinoma in situ of the bladder is arguably the most effective form of tumour immunotherapy described to date. Following repeated instillations of BCG organisms into… Expand
Inflammatory mediators and cervical ripening.
- R. Kelly
- Biology, Medicine
- Journal of reproductive immunology
- 1 October 2002
The mechanisms which soften the cervix and allow it to dilate at birth are not well known. This is a crucial element in labour and current pharmacological approaches, largely the use of… Expand
Decidualization of the human endometrial stromal cell: an enigmatic transformation.
Changes in human endometrium are essential to allow the establishment of pregnancy. These changes are induced in vivo by progesterone, and include appearance within the tissue of a specific uterine… Expand
Progesterone receptor subtype B is differentially regulated in human endometrial stroma.
- H. Wang, H. Critchley, R. Kelly, D. Shen, D. Baird
- Biology, Medicine
- Molecular human reproduction
- 1 April 1998
Two anti-progesterone receptor (PgR) antibodies, a new one specific to PgRB, the other to PgR subtypes A + B, have been used to examine the cellular location of PgR subtypes A and B in normal… Expand
Innate immune defences in the human endometrium
- A. E. King, H. Critchley, R. Kelly
- Medicine, Biology
- Reproductive biology and endocrinology : RB&E
- 28 November 2003
The human endometrium is an important site of innate immune defence, giving protection against uterine infection. Such protection is critical to successful implantation and pregnancy. Infection is a… Expand
Seminal plasma components stimulate interleukin-8 and interleukin-10 release.
Human seminal plasma has potent anti-inflammatory properties which are thought to confer a survival advantage to the spermatozoa within the hostile female genital tract. In contrast, a profound… Expand