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Raxofelast

Known as: 2-(2,3-dihydro-5-acetoxy-4,6,7-trimethylbenzofuranyl)acetic acid, 2-Benzofuranacetic acid, 5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-, (+-)- 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

BenzofuransVitamin E

Narrower (1)

IRFI 016
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Raxofelast, (+/-)5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid: a new antioxidant to modulate the inflammatory response during ischemia-reperfusion injury and impaired wound…
Raxofelast, also named IRFI 016 or (+/-)5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid, belongs to a family of… 
2006
2006
Lipid peroxidation activates mitogen-activated protein kinases in testicular ischemia-reperfusion injury.
2005
2005
Protective Effects of Antioxidant Raxofelast in Alcohol-Induced Liver Disease in Mice
We investigated the effect of raxofelast on lipid peroxidation inhibition in mice exposed to chronic ethanol. Female C57BL/6 mice… 
2005
2005
Raxofelast, a vitamin E analogue, improves angiogenesis and wound healing in experimental burn wounds.
2004
2004
Antiproliferative mechanisms of raxofelast (IRFI-016) in H2O2-stimulated rat aortic smooth muscle cells.
Review
2003
Review
2003
Review Article and Clinical Experience: DIABETES MELLITUS AND ENDOTHELIAL DYSFUNCTION: A CLINICAL APPROACH (Molecular Basis for Clinical Application)
  • 2003
  • Corpus ID: 58446918
SYNDROME-36 (presented in the year 2002) compiled by the Author since 1992 (SYNDROME-11) represents a cluster of 36 components… 
2003
2003
3P-0672 Antiproliferative mechanisms of raxofelast (IRFI-016), a hydrophilic vitamin E-like antioxidant, in H2O2-stimulated rat aortic smooth muscle cells
Highly Cited
1999
Highly Cited
1999
Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E‐like antioxidant, in carrageenan‐induced pleurisy
Peroxynitrite is a strong oxidant that results from reaction between NO and superoxide. It has been recently proposed that… 
1999
1999
Protection of low density lipoprotein oxidation by the antioxidant agent IRFI005, a new synthetic hydrophilic vitamin E analogue.
1998
1998
Beneficial effect of raxofelast, an hydrophilic vitamin E analogue, in the rat heart after ischemia and reperfusion injury.
Several studies report that among the antioxidant agents used to reduce injury after myocardial ischemia/reperfusion, analogues… 
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