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IRFI 016

Known as: IRFI-016 
National Institutes of Health

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1 relation

Broader (1)

Raxofelast

Papers overview

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2005
2005
Antioxidant treatment inhibited glutamate-evoked NF-kappaB activation in primary astroglial cell cultures.
2005
2005
Glutamate promotes NF-κB pathway in primary astrocytes: protective effects of IRFI 016, a synthetic vitamin E analogue
2004
2004
Antiproliferative mechanisms of raxofelast (IRFI-016) in H2O2-stimulated rat aortic smooth muscle cells.
2003
2003
3P-0672 Antiproliferative mechanisms of raxofelast (IRFI-016), a hydrophilic vitamin E-like antioxidant, in H2O2-stimulated rat aortic smooth muscle cells
Highly Cited
1999
Highly Cited
1999
Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E‐like antioxidant, in carrageenan‐induced pleurisy
Peroxynitrite is a strong oxidant that results from reaction between NO and superoxide. It has been recently proposed that… 
1994
1994
Protective effects of IRFI-016, a new antioxidant agent, in myocardial damage, following coronary artery occlusion and reperfusion in the rat.
The new free radical scavenger IRFI-016 [2(2,3-dihydro-5-acetoxy 4,6,7-trimethyl-benzofuranyl) acetic acid] was assessed in a rat… 
1993
1993
A new antioxidant drug limits brain damage induced by transient cerebral ischaemia.
Restoration of blood flow after an ischaemic event generates the formation of oxygen radicals which could augment brain damage… 
1992
1992
IRFI-016, a new radical scavenger, limits ischemic damage following coronary artery occlusion in rats.
The effects of IRFI-016 [2(2,3 Dihydro-5-Acetoxy 4,6,7-Trimethyl-Benzofuranyl) acetic acid] a new radical scavenger were studied… 
1992
1992
Compared kinetics of 2-(2,3-dihydro-5-acetoxy-4,6,7-trimethylbenzofuranyl) acetic acid (IRFI 016) and its active metabolite 2-(2,3-dihydro-5-hydroxy-4,6,7-trimethylbenzofuranyl) acetic acid (IRFI 005…
The concentration of 2-(2,3-dihydro-5-acetoxy-4,6,7-trimethylbenzofuranyl) acetic acid (IRFI 016) and its active metabolite 2-(2… 
1990
1990
2-(2,3-Dihydro-5-acetoxy-4,6,7-tribenzofuranyl)acetic acid (IRFI 016): a new antioxidant mucoactive drug.
IRFI 016 has demonstrated significant antioxidant activity, inhibiting hepatic lipid peroxidation (rat intoxicated by CCl4) and… 
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