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RX-781094

Known as: RX 781094, RX781094 
National Institutes of Health

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Broader (1)

Idazoxan

Papers overview

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Highly Cited
1988
Highly Cited
1988
Antinociceptive actions of descending dopaminergic tracts on cat and rat dorsal horn somatosensory neurones.
1. The actions of dopamine (DA) and DA receptor specific agonists and antagonist ionophoretically applied in the spinal dorsal… 
Highly Cited
1985
Highly Cited
1985
An α2 receptor mediates the selective inhibition by noradrenaline of nociceptive responses of identified dorsal horn neurones
Highly Cited
1985
Highly Cited
1985
Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons
Extracellular single-cell recording techniques were employed to study the mechanism of action of repeated oral clozapine… 
Highly Cited
1985
Highly Cited
1985
Inhibitory synaptic potentials resulting from alpha 2‐adrenoceptor activation in guinea‐pig submucous plexus neurones.
Intracellular recordings were obtained from neurones of the guinea‐pig submucous plexus. Inhibitory synaptic potentials (i.p.s.p… 
Highly Cited
1984
Highly Cited
1984
A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors.
In a comparative study using various in vivo and in vitro models, the alpha-1/alpha-2 adrenoceptor blocking potencies and… 
1984
1984
Postsynaptic alpha 2-adrenergic receptor-mediated vasoconstriction in SHR tail arteries in vitro.
In isolated perfused tail arteries of spontaneously hypertensive rats (SHR), the selective alpha 2-adrenergic receptor antagonist… 
1984
1984
Tizanidine (DS103-282), a centrally acting muscle relaxant, selectively depresses excitation of feline dorsal horn neurones to noxious peripheral stimuli by an action at α 2-adrenoceptors
Highly Cited
1983
Highly Cited
1983
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors.
1 The selectivity and specificity of RX 781094 [2-(2-(1,4 benzodioxanyl))2-imidazoline HCl] for alpha-adrenoceptors have been… 
Highly Cited
1983
Highly Cited
1983
Evidence for postjunctional vascular alpha 2-adrenoceptors in peripheral vascular regulation in man.
Preliminary studies in healthy normotensive subjects with a selective alpha 2-adrenoceptor antagonist 2-[2-(1,4-benzodioxanyl)]-2… 
1982
1982
Reversal of clonidine induced miosis by the alpha 2-adrenoreceptor antagonist RX 781094.
Clonidine given i.v. at a dose of 0.1 mg and 0.2 mg was found to cause miosis in a placebo controlled double-blind study in six… 
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