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RX-781094
Known as:
RX 781094
, RX781094
National Institutes of Health
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1 relation
Broader (1)
Idazoxan
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Highly Cited
1988
Highly Cited
1988
Antinociceptive actions of descending dopaminergic tracts on cat and rat dorsal horn somatosensory neurones.
S. Fleetwood-Walker
,
P. J. Hope
,
R. Mitchell
The Journal of physiology
1988
Corpus ID: 23605415
1. The actions of dopamine (DA) and DA receptor specific agonists and antagonist ionophoretically applied in the spinal dorsal…
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Highly Cited
1985
Highly Cited
1985
An α2 receptor mediates the selective inhibition by noradrenaline of nociceptive responses of identified dorsal horn neurones
S. Fleetwood-Walker
,
R. Mitchell
,
P. J. Hope
,
V. Molony
,
A. Iggo
Brain Research
1985
Corpus ID: 690414
Highly Cited
1985
Highly Cited
1985
Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons
L. Chiodo
,
B. Bunney
The Journal of neuroscience : the official…
1985
Corpus ID: 17700609
Extracellular single-cell recording techniques were employed to study the mechanism of action of repeated oral clozapine…
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Highly Cited
1985
Highly Cited
1985
Inhibitory synaptic potentials resulting from alpha 2‐adrenoceptor activation in guinea‐pig submucous plexus neurones.
R. North
,
A. Surprenant
The Journal of physiology
1985
Corpus ID: 30258527
Intracellular recordings were obtained from neurones of the guinea‐pig submucous plexus. Inhibitory synaptic potentials (i.p.s.p…
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Highly Cited
1984
Highly Cited
1984
A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors.
P. Timmermans
,
J. Qian
,
R. Ruffolo
,
P. V. van Zwieten
The Journal of pharmacology and experimental…
1984
Corpus ID: 776339
In a comparative study using various in vivo and in vitro models, the alpha-1/alpha-2 adrenoceptor blocking potencies and…
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1984
1984
Postsynaptic alpha 2-adrenergic receptor-mediated vasoconstriction in SHR tail arteries in vitro.
P. Hicks
,
I. C. Medgett
,
S. Z. Langer
Hypertension
1984
Corpus ID: 42724072
In isolated perfused tail arteries of spontaneously hypertensive rats (SHR), the selective alpha 2-adrenergic receptor antagonist…
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1984
1984
Tizanidine (DS103-282), a centrally acting muscle relaxant, selectively depresses excitation of feline dorsal horn neurones to noxious peripheral stimuli by an action at α 2-adrenoceptors
J. Davies
,
S. Johnston
,
D. Hill
,
J. E. Quinlan
Neuroscience Letters
1984
Corpus ID: 31987802
Highly Cited
1983
Highly Cited
1983
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors.
J. Doxey
,
A. Roach
,
C. Smith
British journal of pharmacology
1983
Corpus ID: 19869873
1 The selectivity and specificity of RX 781094 [2-(2-(1,4 benzodioxanyl))2-imidazoline HCl] for alpha-adrenoceptors have been…
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Highly Cited
1983
Highly Cited
1983
Evidence for postjunctional vascular alpha 2-adrenoceptors in peripheral vascular regulation in man.
H. Elliott
,
J. Reid
Clinical science
1983
Corpus ID: 42327831
Preliminary studies in healthy normotensive subjects with a selective alpha 2-adrenoceptor antagonist 2-[2-(1,4-benzodioxanyl)]-2…
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1982
1982
Reversal of clonidine induced miosis by the alpha 2-adrenoreceptor antagonist RX 781094.
J. M. Clifford
,
M. D. Day
,
J. Orwin
British journal of clinical pharmacology
1982
Corpus ID: 41643673
Clonidine given i.v. at a dose of 0.1 mg and 0.2 mg was found to cause miosis in a placebo controlled double-blind study in six…
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