Pre- and postsynaptic actions of noradrenaline and clonidine on myenteric neurons

@article{Slack1986PreAP,
  title={Pre- and postsynaptic actions of noradrenaline and clonidine on myenteric neurons},
  author={B. Slack},
  journal={Neuroscience},
  year={1986},
  volume={19},
  pages={1303-1309}
}
  • B. Slack
  • Published 1986
  • Medicine, Chemistry
  • Neuroscience
alpha-2 adrenergic agonists inhibit nicotinic excitatory postsynaptic potentials and reduce calcium dependent action potentials in myenteric neurons. To test the hypothesis that adrenergic inhibitory effects on action potential configuration and on inhibition of acetylcholine release from the nerve terminal are analogous processes, the pharmacological characteristics and underlying mechanisms of these two effects were compared in neurons of the myenteric plexus in the guinea pig. Both clonidine… Expand
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