J. Malick

Publications71
h-index24
Citations1,892
Highly Influential Citations22
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  • Publications
  • Influence
Analgesic activity of substance P following intracerebral administration in rats.
The pharmacology of isolation-induced aggressive behavior in mice.
  • J. Malick
  • Biology, Psychology
    Current developments in psychopharmacology
  • 1979
TLDR
This review attempts to summarize the literature on the effects of drugs on isolation-induced aggression in mice and concludes that statements concerning drug selectivity or specificity are meaningless without some evidence for a lack of neurological impairment in isolated, aggressive mice.
Quipazine-induced head-twitch in mice
The evaluation of anti-parkinson drugs on reserpine-induced rigidity in rats.
Drug Discovery and Development
TLDR
The process of drug discovery involves a melding of many disciplines and interests, transcending the relatively simple process of identifying an active compound in the test tube and must be relatively free of toxicity, bioavailable, and marketable before it can be considered to be a therapeutic entity.
Seroquel: electrophysiological profile of a potential atypical antipsychotic
TLDR
In cell population studies, acute treatment with seroquel and clozapine selectively increased the number of spontaneously active A10 DA cells, which was found to correlate with the ability of both these drugs to cause depolarization inactivation (DI) of A10DA cells following repeated (28 day) administration.
Novel non-benzodiazepine anxiolytics
Differential antagonism of the anticonflict effects of typical and atypical anxiolytics.
ICI 204,636, a novel, atypical antipsychotic: early indication of safety and efficacy in patients with chronic and subchronic schizophrenia.
Effects of isoproterenol and chlordiazepoxide on drinking and conflict behaviors in rats
  • J. Patel, J. Malick
  • Psychology, Biology
    Pharmacology Biochemistry and Behavior
  • 1 May 1980
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