Idazoxan

Known as: Idazoxan [Chemical/Ingredient] 
A benzodioxane-linked imidazole that has alpha-2 adrenoceptor antagonist activity.
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
Methylphenidate (MPH) is the classic treatment for Attention Deficit Hyperactivity Disorder (ADHD), yet the mechanisms underlying… (More)
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Highly Cited
2001
Highly Cited
2001
Dyskinesia is a frequent and disabling side effect in patients with Parkinson's disease treated with chronic dopa-therapy… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND We investigated whether antagonism of alpha 2 adrenergic receptors would augment treatment response in schizophrenia… (More)
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Highly Cited
1994
Highly Cited
1994
When mice are introduced into an open-field, they are inclined to explore mainly the peripheral zone of this open-field. This… (More)
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Highly Cited
1993
Highly Cited
1993
Previous studies have indicated a noradrenergic modulation of midbrain dopamine cell activity. The effects of systemic… (More)
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Highly Cited
1992
Highly Cited
1992
Various classes of antidepressant drugs with distinct pharmacologic actions are differentially effective in the treatment of… (More)
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Highly Cited
1991
Highly Cited
1991
Experiments were conducted to examine the hypothesis that increased neuronal discharge activity of noradrenergic neurons of the… (More)
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Highly Cited
1987
Highly Cited
1987
Transcortical dialysis in awake unrestrained rats has been used to evaluate the functional role of differently located alpha-2… (More)
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Highly Cited
1984
Highly Cited
1984
An elevated X-maze with alternating open and enclosed arms was investigated as a model for the study of fear-induced behaviour… (More)
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1984
1984
We have studied the alpha-adrenoceptor antagonist effects of idazoxan (RX 781094) in extracellular recordings from single locus… (More)
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