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RX-3117

Known as: Cytidine Analog RX-3117 
An orally available small molecule and nucleoside antimetabolite with potential antineoplastic activity. Upon administration, the cytidine analog RX… Expand
National Institutes of Health

Papers overview

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2019
2019
Background/Aim: The novel cytidine analog RX-3117, which is activated by uridine-cytidine kinase 2 (UCK2), shows encouraging… Expand
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2019
2019
Background: RX-3117 is an oral, small molecule nucleoside analogue pro-drug being used in combination with nab-paclitaxel in a… Expand
2018
2018
Abstract DNA methylation plays an important role in carcinogenesis and aberrant methylation patterns have been found in many… Expand
2016
2016
Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has… Expand
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2016
2016
ABSTRACT RX-3117 (fluorocyclopentenyl-cytosine) is a novel cytidine analog currently being evaluated in a Phase Ib clinical trial… Expand
2015
2015
Fluorocyclopentenylcytosine (RX-3117) is an orally bioavailable novel cytidine analog, currently being tested in a Phase I… Expand
2015
2015
e13545 Background: RX-3117 (fluorocyclopentenylcytosine) is a novel antimetabolite, that requires activation by uridine-cytidine… Expand
Review
2014
Review
2014
  • G. Peters
  • Nucleosides, nucleotides & nucleic acids
  • 2014
  • Corpus ID: 205855349
Antimetabolites are the most widely used and most efficacious group of anticancer drugs. Antimetabolites are also the oldest… Expand
2014
2014
RX-3117 (fluorocyclopentenylcytosine) is a cytidine analog and this class of drugs, including gemcitabine, has been widely used… Expand
2013
2013
SummaryA novel cytidine analog fluorocyclopentenylcytosine (RX-3117; TV-1360) was characterized for its cytotoxicity in a 59-cell… Expand
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