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RX-3117
Known as:
Cytidine Analog RX-3117
An orally available small molecule and nucleoside antimetabolite with potential antineoplastic activity. Upon administration, the cytidine analog RX…
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National Institutes of Health
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Related topics
Related topics
5 relations
DNA Synthesis Inhibition
Nucleotide Biosynthesis
Positive Regulation of Apoptosis
Ribonucleotide Reductase
Broader (1)
fluorocyclopentenylcytosine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 428: Phenotyping pancreatic cancer CTCs as biomarkers for RX-3117 clinical trials
A. Eisen
,
Dj Kim
,
Jie Yang
,
Weiguo Wu
,
D. Davis
Clinical research
2019
Corpus ID: 203832918
Background: RX-3117 is an oral, small molecule nucleoside analogue pro-drug being used in combination with nab-paclitaxel in a…
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2017
2017
Abstract 1790: Evaluation of UCK2 protein expression as a potential predictive biomarker of RX-3117
Y. Lee
,
Deog Joong Kim
,
+5 authors
Eric P. Olsen
2017
Corpus ID: 80458670
Background: A novel, orally bioavailable nucleoside analogue, RX-3117, is a prodrug activated intracellularly by Uridine Cytidine…
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