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RX-3117

Known as: Cytidine Analog RX-3117 
An orally available small molecule and nucleoside antimetabolite with potential antineoplastic activity. Upon administration, the cytidine analog RX… Expand
National Institutes of Health

Papers overview

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2019
2019
Background: RX-3117 is an oral, small molecule nucleoside analogue pro-drug being used in combination with nab-paclitaxel in a… Expand
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Review
2019
Review
2019
INTRODUCTION RX-3117 is an oral, small molecule cytidine analog anticancer agent with an improved pharmacological profile… Expand
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2018
2018
DNA methylation plays an important role in carcinogenesis and aberrant methylation patterns have been found in many tumors… Expand
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2016
2016
Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has… Expand
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2016
2016
RX-3117 (fluorocyclopentenyl-cytosine) is a novel cytidine analog currently being evaluated in a Phase Ib clinical trial in… Expand
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2015
2015
Fluorocyclopentenylcytosine (RX-3117) is an orally bioavailable novel cytidine analog, currently being tested in a Phase I… Expand
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2015
2015
e13545 Background: RX-3117 (fluorocyclopentenylcytosine) is a novel antimetabolite, that requires activation by uridine-cytidine… Expand
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2014
2014
RX-3117 (fluorocyclopentenylcytosine) is a cytidine analog and this class of drugs, including gemcitabine, has been widely used… Expand
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Review
2014
Review
2014
Antimetabolites are the most widely used and most efficacious group of anticancer drugs. Antimetabolites are also the oldest… Expand
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2013
2013
SummaryA novel cytidine analog fluorocyclopentenylcytosine (RX-3117; TV-1360) was characterized for its cytotoxicity in a 59-cell… Expand
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