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fluorocyclopentenylcytosine

Known as: 4-Amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl)pyrimidin-2(1H)-one 
 
National Institutes of Health

Papers overview

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2019
2019
RX-3117 is a novel cytidine analog showing encouraging results in ongoing Phase 2a studies with gemcitabine-resistant pancreatic… Expand
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2018
2018
DNA methylation plays an important role in carcinogenesis and aberrant methylation patterns have been found in many tumors… Expand
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2016
2016
Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has… Expand
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2016
2016
Antimetabolites are incorporated into DNA and RNA, affecting their function. Liquid-chromatography-mass-spectrometry (LC-MS-MS… Expand
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2015
2015
Fluorocyclopentenylcytosine (RX-3117) is an orally bioavailable novel cytidine analog, currently being tested in a Phase I… Expand
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Review
2014
Review
2014
Antimetabolites are the most widely used and most efficacious group of anticancer drugs. Antimetabolites are also the oldest… Expand
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2014
2014
RX-3117 (fluorocyclopentenylcytosine) is a cytidine analog and this class of drugs, including gemcitabine, has been widely used… Expand
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2013
2013
SummaryA novel cytidine analog fluorocyclopentenylcytosine (RX-3117; TV-1360) was characterized for its cytotoxicity in a 59-cell… Expand
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