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Nucleotide Biosynthesis

Known as: nucleotide biosynthetic process, Nucleotide Synthesis Alteration, nucleotide anabolism 
The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an… Expand
National Institutes of Health

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34 relations
5-Hydroxytryptamine Receptor 2C, humanATIC geneATIC wt AlleleATP5B gene
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nucleoside kinase activity

Papers overview

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Highly Cited
2016
Highly Cited
2016
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth
The Hippo pathway is an important regulator of organ size and tumorigenesis. It is unclear, however, how Hippo signalling… Expand
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Highly Cited
2014
Highly Cited
2014
Protein and Nucleotide Biosynthesis Are Coupled by a Single Rate-Limiting Enzyme, PRPS2, to Drive Cancer
Cancer cells must integrate multiple biosynthetic demands to drive indefinite proliferation. How these key cellular processes… Expand
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Highly Cited
2013
Highly Cited
2013
Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies.
A common thread among conserved life span regulators lies within intertwined roles in metabolism and energy homeostasis. We show… Expand
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Highly Cited
2011
Highly Cited
2011
Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
Chromosomal instability in early cancer stages is caused by stress on DNA replication. The molecular basis for replication… Expand
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Highly Cited
2008
Highly Cited
2008
Nucleotide Biosynthesis Is Critical for Growth of Bacteria in Human Blood
Proliferation of bacterial pathogens in blood represents one of the most dangerous stages of infection. Growth in blood serum… Expand
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Review
2004
Review
2004
Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen.
Transcriptome analysis, using Affymetrix ATH1 arrays and a real-time reverse transcription-PCR platform for >1,400 transcription… Expand
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Highly Cited
2004
Highly Cited
2004
Gene transfer in the evolution of parasite nucleotide biosynthesis.
Nucleotide metabolic pathways provide numerous successful targets for antiparasitic chemotherapy, but the human pathogen… Expand
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Review
2004
Review
2004
The concentrative nucleoside transporter family, SLC28
The SLC28 family consists of three subtypes of sodium-dependent, concentrative nucleoside transporters, CNT1, CNT2, and CNT3… Expand
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Highly Cited
2002
Highly Cited
2002
Purine and Pyrimidine Nucleotide Synthesis and Metabolism
Purine and pyrimidine nucleotides are major energy carriers, subunits of nucleic acids and precursors for the synthesis of… Expand
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Review
1980
Review
1980
Pyrimidine nucleotide biosynthesis in animals: genes, enzymes, and regulation of UMP biosynthesis.
PERSPECfIVES AND SUMMARY 253 INTRODUCfION 256 GENES AND PROTEIN PRODUCfS 257 Drosophila 257 Mammals 258 Multienzyme pyr1-3 258… Expand
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