ATIC wt Allele

Known as: IMPCHASE, Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase Gene, AICAR 
Human ATIC wild-type allele is located in the vicinity of 2q35 and is approximately 38 kb in length. This allele, which encodes bifunctional purine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
01219892017

Papers overview

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2018
2018
Aminoimidazolecarboxamide ribonucleotide formyl transferase (AICARFT): Inosine monophosphate cyclohydrolase (IMPCH, collectively… (More)
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2017
2017
A hallmark of cancer is unbridled proliferation that can result in increased demand for de novo synthesis of purine and… (More)
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2013
2013
BACKGROUND Malignant mesothelioma is a highly aggressive tumor arising from mesothelial-lined surfaces, most often in the pleura… (More)
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2009
2009
The class Gammaproteobacteria, which forms one of the largest groups within bacteria, is currently distinguished from other… (More)
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2005
2005
Undomesticated strains of Bacillus subtilis exhibit extensive colony spreading on certain soft agarose media: first the formation… (More)
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2000
2000
It has been proposed that the clinical utility of methotrexate (MTX) in the treatment of rheumatoid arthritis may be due, in part… (More)
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2000
2000
Regulated alternative splicing of avian cardiac troponin T (cTNT) pre-mRNA requires multiple intronic elements called muscle… (More)
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1996
1996
We report here the cloning and sequencing of the cDNA, purification, steady state kinetic analysis, and truncation mapping… (More)
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1995
1995
The de novo purine synthesis inhibitor 5,10-dideazatetrahydrofolate (DDATHF) has previously been shown to inhibit the growth of… (More)
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1989
1989
In order to determine the biochemical basis for the cytotoxicity of homofolates, poly-gamma-glutamyl derivatives of homofolate… (More)
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