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ATIC wt Allele

Known as: IMPCHASE, Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase Gene, AICAR 
Human ATIC wild-type allele is located in the vicinity of 2q35 and is approximately 38 kb in length. This allele, which encodes bifunctional purine… 
National Institutes of Health

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4 relations
2q35ATIC geneHydrolysisNucleotide Biosynthesis

Papers overview

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2018
2018
Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia…
Dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase (PurH… 
2017
2017
Transient and dynamic DNA supercoiling potently stimulates the leu-500 promoter in Escherichia coli
The inactive prokaryotic leu-500 promoter (Pleu-500) contains a single A-to-G point mutation in the −10 region of the leucine… 
2014
2014
Cahiers historiques des Annales de droit, n° 1, David Hoüard (1725-1802). Un juriste en son temps. PURH, 2012
Ce premier numero qui inaugure une collection destinee a « faire connaitre les rencontres autour de l’histoire du droit… 
2013
2013
Construire les liens de famille dans l'Europe moderne
2011
2011
Compte-rendu de lecture de : « Emmanuel Dupraz : Les Vestins à l'époque tardo-républicaine, Du Nord-Osque au latin. Mont-Saint-Aignan : PURH, 2010. »
2011
2011
Takagaki Yumi, (2011), De la rhetorique contrastive a la linguistique textuelle. L'organisation textuelle du francais et du japonais, Osaka Rouen Le Havre, OMUP (Osaka Municipal Universities Press…
Highly Cited
2009
Highly Cited
2009
Phylogenomics and protein signatures elucidating the evolutionary relationships among the Gammaproteobacteria.
The class Gammaproteobacteria, which forms one of the largest groups within bacteria, is currently distinguished from other… 
Highly Cited
1996
Highly Cited
1996
The Human purH Gene Product, 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase
We report here the cloning and sequencing of the cDNA, purification, steady state kinetic analysis, and truncation mapping… 
1989
1989
Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts.
In order to determine the biochemical basis for the cytotoxicity of homofolates, poly-gamma-glutamyl derivatives of homofolate… 
1975
1975
Biochemical characterization and genetic mapping of purine genes in Micrococcus luteus.
Purine auxotrophs of Micrococcus luteus were induced by N -methyl- N ′-nitro- N -nitrosoguanidine. They were biochemically… 
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