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Ribonucleotide Reductase

Known as: EC 1.17.4.-, Ribonucleotide Reductases [Chemical/Ingredient], Ribonucleotide Reductases 
Ribonucleotide Reductase is a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide… 
National Institutes of Health

Related topics

Related topics

39 relations

Broader (2)

Alcohol OxidoreductasesIron-Sulfur Proteins
DNA ReplicationFludarabine phosphateGemcitabine ElaidateGemcitabine hydrochloride

Narrower (10)

ICP10 protein, herpes simplex virus type 2NrdB protein, E coliNrdF protein, E coliNrdF protein, bacteria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
The chemistry and biochemistry of the copper–radical interaction
This Perspective describes the plausible oxidation state combinations of Cun/Lm systems where Lm is an O- or N-based redox system… 
Highly Cited
1996
Highly Cited
1996
Two Conserved Tyrosine Residues in Protein R1 Participate in an Intermolecular Electron Transfer in Ribonucleotide Reductase*
The enzyme ribonucleotide reductase consists of two nonidentical proteins, R1 and R2, which are each inactive alone. R1 contains… 
Highly Cited
1996
Highly Cited
1996
The Anaerobic Escherichia coli Ribonucleotide Reductase
During anaerobic growth Escherichia coli uses a specific ribonucleoside triphosphate reductase for the production of… 
Highly Cited
1991
Highly Cited
1991
Purification and characterization of recombinant mouse and herpes simplex virus ribonucleotide reductase R2 subunit.
Overexpression of recombinant mouse and herpes simplex virus ribonucleotide reductase small subunit (protein R2) has been… 
Highly Cited
1988
Highly Cited
1988
Ribonucleotide reductase of Brevibacterium ammoniagenes is a manganese enzyme.
Ribonucleotide reduction and not DNA replication is the site for the specific manganese requirement of DNA synthesis and cell… 
Highly Cited
1988
Highly Cited
1988
Ribonucleotide reductase encoded by herpes simplex virus is a determinant of the pathogenicity of the virus in mice and a valid antiviral target.
The role of the herpes simplex virus (HSV)-encoded ribonucleotide reductase (RR) in the pathogenicity of the virus has been… 
Highly Cited
1987
Highly Cited
1987
Magnetic interaction between the tyrosyl free radical and the antiferromagnetically coupled iron center in ribonucleotide reductase.
Ribonucleotide reductases from Escherichia coli and from mammalian cells are heterodimeric enzymes. One of the subunits, in the… 
Highly Cited
1983
Highly Cited
1983
Ribonucleotide reductase induced by herpes simplex virus has a virus-specified constituent.
Ribonucleotide reductase, an enzyme found in all prokaryotic and eukaryotic cells that synthesize DNA, is induced by herpes… 
Highly Cited
1977
Highly Cited
1977
Nature of the free radical in ribonucleotide reductase from Escherichia coli.
Ribonucleotide reductase from Escherichia coli consists of two nonidentical subunits, proteins B1 and B2. The active site of the… 
Highly Cited
1966
Highly Cited
1966
Regulation of mammalian deoxyribonucleotide biosynthesis by nucleotides as activators and inhibitors.
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