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Ribonucleotide Reductase

Known as: EC 1.17.4.-, Ribonucleotide Reductases [Chemical/Ingredient], Ribonucleotide Reductases 
Ribonucleotide Reductase is a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide… Expand
National Institutes of Health

Related topics

Related topics

39 relations

Broader (2)

Alcohol OxidoreductasesIron-Sulfur Proteins
DNA ReplicationFludarabine phosphateGemcitabine ElaidateGemcitabine hydrochloride
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Narrower (10)

ICP10 protein, herpes simplex virus type 2NrdB protein, E coliNrdF protein, E coliNrdF protein, bacteria
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Structure, function, and mechanism of ribonucleotide reductases.
Ribonucleotide reductase (RNR) is the enzyme responsible for the conversion of ribonucleotides to 2'-deoxyribonucleotides and… Expand
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Highly Cited
2003
Highly Cited
2003
Survival of DNA Damage in Yeast Directly Depends on Increased dNTP Levels Allowed by Relaxed Feedback Inhibition of Ribonucleotide Reductase
In eukaryotes, DNA damage elicits a multifaceted response that includes cell cycle arrest, transcriptional activation of DNA… Expand
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Review
2000
Review
2000
Physiological functions of thioredoxin and thioredoxin reductase.
Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from Archea to man. Thioredoxins, with a… Expand
Review
1998
Review
1998
Ribonucleotide reductases.
Ribonucleotide reductases provide the building blocks for DNA replication in all living cells. Three different classes of enzymes… Expand
Highly Cited
1998
Highly Cited
1998
Resveratrol, a remarkable inhibitor of ribonucleotide reductase
Resveratrol, a natural phytoalexin found in grapes, is well known for its presumed role in the prevention of heart disease… Expand
Highly Cited
1994
Highly Cited
1994
Structure of ribonucleotide reductase protein R1
Ribonucleotide reductase is the only enzyme that catalyses de novo formation of deoxyribo-nucleotides and is thus a key enzyme in… Expand
Highly Cited
1993
Highly Cited
1993
From RNA to DNA, why so many ribonucleotide reductases?
It is generally accepted that DNA appeared after RNA during the chemical evolution of life. To synthesize DNA… Expand
Highly Cited
1991
Highly Cited
1991
Inactivation of ribonucleotide reductase by nitric oxide.
Ribonucleotide reductase has been demonstrated to be inhibited by NO synthase product(s). The experiments reported here show that… Expand
Highly Cited
1990
Highly Cited
1990
Three-dimensional structure of the free radical protein of ribonucleotide reductase
The enzyme ribonucleotide reductase furnishes precursors for the DNA synthesis of all living cells. One of its constituents, the… Expand
Highly Cited
1984
Highly Cited
1984
DNA sequence and expression of the B95-8 Epstein—Barr virus genome
The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the… Expand
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