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Ribonucleotide Reductase

Known as: EC 1.17.4.-, Ribonucleotide Reductases [Chemical/Ingredient], Ribonucleotide Reductases 
Ribonucleotide Reductase is a heterodimeric cytoplasmic enzyme essential in dividing cells that reduces ribonucleotides to deoxyribonucleotide… 
National Institutes of Health

Related topics

Related topics

39 relations

Broader (2)

Alcohol OxidoreductasesIron-Sulfur Proteins
DNA ReplicationFludarabine phosphateGemcitabine ElaidateGemcitabine hydrochloride

Narrower (10)

ICP10 protein, herpes simplex virus type 2NrdB protein, E coliNrdF protein, E coliNrdF protein, bacteria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The thioredoxin antioxidant system.
Review
2009
Review
2009
Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors.
Iron chelators have potential therapeutic use for the treatment of cancer. Studies with a range of chelators indicate that Fe… 
Review
2006
Review
2006
Ribonucleotide reductases.
Ribonucleotide reductases (RNRs) transform RNA building blocks to DNA building blocks by catalyzing the substitution of the 2'OH… 
Review
2006
Review
2006
Ribonucleotide reductase inhibitors and future drug design.
Ribonucleotide reductase (RR) is a multisubunit enzyme responsible for the reduction of ribonucleotides to their corresponding… 
Review
2003
Review
2003
Radical initiation in the class I ribonucleotide reductase: long-range proton-coupled electron transfer?
Review
2000
Review
2000
Physiological functions of thioredoxin and thioredoxin reductase.
Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from Archea to man. Thioredoxins, with a… 
Highly Cited
1994
Highly Cited
1994
Structure of ribonucleotide reductase protein R1
Ribonucleotide reductase is the only enzyme that catalyses de novo formation of deoxyribo-nucleotides and is thus a key enzyme in… 
Highly Cited
1990
Highly Cited
1990
Three-dimensional structure of the free radical protein of ribonucleotide reductase
The enzyme ribonucleotide reductase furnishes precursors for the DNA synthesis of all living cells. One of its constituents, the… 
Highly Cited
1990
Highly Cited
1990
Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase.
Ribonucleotide reductase activity is essential for progression through the cell cycle, catalyzing the rate-limiting step for the… 
Highly Cited
1984
Highly Cited
1984
DNA sequence and expression of the B95-8 Epstein—Barr virus genome
The complete (172,282 base pairs) nucleotide sequence of the B95-8 strain of Epstein–Barr virus has been established using the… 
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