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RTI-55
Known as:
RTI 55
National Institutes of Health
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Highly Cited
2006
Highly Cited
2006
Tyr-95 and Ile-172 in Transmembrane Segments 1 and 3 of Human Serotonin Transporters Interact to Establish High Affinity Recognition of Antidepressants*
L. Henry
,
J. Field
,
+5 authors
R. Blakely
Journal of Biological Chemistry
2006
Corpus ID: 25851403
In previous studies examining the structural determinants of antidepressant and substrate recognition by serotonin transporters…
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Highly Cited
2004
Highly Cited
2004
Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.
Chong-Bin Zhu
,
W. Hewlett
,
I. Feoktistov
,
I. Biaggioni
,
R. Blakely
Molecular pharmacology
2004
Corpus ID: 32280330
Serotonin (5-hydroxytryptamine; 5-HT) transporters (SERTs) are critical determinants of synaptic 5-HT inactivation and the…
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2001
2001
Mechanisms of cocaine-induced decreases in immune cell function.
T. Pellegrino
,
K. Dunn
,
B. Bayer
International immunopharmacology
2001
Corpus ID: 23911573
2001
2001
Locomotor stimulant effects of novel phenyltropanes in the mouse.
H. Kimmel
,
F. Carroll
,
M. Kuhar
Drug and alcohol dependence
2001
Corpus ID: 46212104
Highly Cited
1999
Highly Cited
1999
Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type.
A. Eshleman
,
M. Carmolli
,
M. Cumbay
,
C. Martens
,
K. Neve
,
A. Janowsky
The Journal of pharmacology and experimental…
1999
Corpus ID: 23280602
We characterized the effects of drugs on the uptake of [3H]neurotransmitter by and the binding of [125I](3beta-(4-iodophenyl…
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1998
1998
Positron emission tomography radioligands for dopamine transporters and studies in human and nonhuman primates.
N. Volkow
,
J. Fowler
,
Y. Ding
,
G. Wang
,
S. Gatley
Advances in pharmacology
1998
Corpus ID: 31227517
1996
1996
Cocaine cross-sensitization to dopamine uptake inhibitors: Unique effects of GBR12909
G. Elmer
,
A. Brockington
,
+5 authors
R. Rothman
Pharmacology Biochemistry and Behavior
1996
Corpus ID: 24502654
Highly Cited
1994
Highly Cited
1994
Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.
L. Demchyshyn
,
Z. Pristupa
,
+5 authors
H. Niznik
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 28651949
We report here on the isolation and characterization of a serotonin (5HT) transporter from Drosophila melanogaster. A 3.1-kb…
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Highly Cited
1994
Highly Cited
1994
Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55.
R. Rothman
,
J. Cadet
,
+7 authors
J. Wang
The Journal of pharmacology and experimental…
1994
Corpus ID: 20476852
The drug 3 beta-[4'-iodophenyl]tropan-2 beta-carboxylic acid methyl ester (RTI-55) is a cocaine congener with high affinity for…
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Highly Cited
1993
Highly Cited
1993
[125I]RTI‐55 Binding to Cocaine‐Sensitive Dopaminergic and Serotonergic Uptake Sites in the Human Brain
K. Y. Little
,
J. Kirkman
,
F. Carroll
,
G. Breese
,
G. Duncan
Journal of neurochemistry
1993
Corpus ID: 22257761
[125I]RTI‐55 is a newly synthesized cocaine congener that may offer advantages over other ligands previously used to examine…
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