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RTI-55

Known as: RTI 55 
 

Topic mentions per year

Topic mentions per year

1992-2016
02419922016

Papers overview

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Highly Cited
2006
Highly Cited
2006
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
In previous studies examining the structural determinants of antidepressant and substrate recognition by serotonin transporters… (More)
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Highly Cited
2004
Highly Cited
2004
Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.
Serotonin (5-hydroxytryptamine; 5-HT) transporters (SERTs) are critical determinants of synaptic 5-HT inactivation and the… (More)
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1997
1997
A simple probe measures the pharmacokinetics of[125I]RTI-55 in mouse brain in vivo.
A simple external radiation detector system was used to assess brain dopamine and serotonin transporters in mice in vivo using… (More)
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1996
1996
Displacement of RTI-55 from the dopamine transporter by cocaine.
The cocaine analog 3 beta-(4-iodophenyl)tropane-2 beta-carboxylic acid methyl ester (RTI-55 or beta CIT) has a higher affinity… (More)
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1994
1994
Distribution of cocaine recognition sites in rat brain: in vitro and ex vivo autoradiography with [125I]RTI-55.
The distribution of binding sites of [125I]RTI-55 (3 beta-(4-iodophenyl)tropan-2 beta-carboxylic acid methyl ester), a phenyl… (More)
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1994
1994
Studies of the biogenic amine transporters. IV. Demonstration of a multiplicity of binding sites in rat caudate membranes for the cocaine analog [125I]RTI-55.
The drug 3 beta-[4'-iodophenyl]tropan-2 beta-carboxylic acid methyl ester (RTI-55) is a cocaine congener with high affinity for… (More)
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1994
1994
Cloning, expression, and localization of a chloride-facilitated, cocaine-sensitive serotonin transporter from Drosophila melanogaster.
We report here on the isolation and characterization of a serotonin (5HT) transporter from Drosophila melanogaster. A 3.1-kb… (More)
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1993
1993
[125I]RTI-55 binding to cocaine-sensitive dopaminergic and serotonergic uptake sites in the human brain.
[125I]RTI-55 is a newly synthesized cocaine congener that may offer advantages over other ligands previously used to examine… (More)
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1992
1992
High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.
RTI-55 (3 beta-(4-iodophenyl)tropan-2 beta-carboxylic acid methyl ester), one of the most potent inhibitors of dopamine uptake… (More)
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1992
1992
Distribution of cocaine recognition sites in monkey brain: II. Ex vivo autoradiography with [3H]CFT and [125I]RTI-55.
CFT [WIN 35,428, 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] and its 4-iodinated analog RTI-55 have been proposed as… (More)
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