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RNA-Directed DNA Polymerase

Known as: RNA Transcriptase, Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed), DNA Polymerase, RNA Directed 
An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49… 
National Institutes of Health

Related topics

Related topics

30 relations

Broader (2)

DNA Nucleotidyltransferasesnucleotidyltransferase
DNA-Directed RNA PolymeraseEnzyme GeneGene Products, polHIV nonnucleoside reverse transcriptase gene mutations detected:Prid:Pt:Isolate:Nom

Narrower (6)

LtrA protein, Lactococcus lactisaI1 endonucleaseaI2 protein, S cerevisiaematurase I-AniI

Papers overview

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Highly Cited
2001
Highly Cited
2001
Lack of evidence of endogenous avian leukosis virus and endogenous avian retrovirus transmission to measles, mumps, and rubella vaccine recipients.
The identification of endogenous avian leukosis virus (ALV) and endogenous avian retrovirus (EAV) in chick cell-derived measles… 
Highly Cited
1995
Highly Cited
1995
Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication
HBY 097 [(S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3, 4-dihydroquinoxaline-2(1H)-thione] was selected from a series… 
Highly Cited
1991
Highly Cited
1991
The particle size of hepatitis C virus estimated by filtration through microporous regenerated cellulose fibre.
To estimate the particle size of hepatitis C virus (HCV), a major causative agent of post-transfusion non-A, non-B hepatitis, we… 
Highly Cited
1987
Highly Cited
1987
The vinyl chloride-derived nucleoside, N2,3-ethenoguanosine, is a highly efficient mutagen in transcription.
N2,3-Ethenoguanine (N2,3-epsilon G) was recently identified in the liver of vinyl chloride-exposed rats. We have now synthesized… 
Highly Cited
1985
Highly Cited
1985
A novel expression selection approach allows precise mapping of the hepatitis B virus enhancer.
We have used a novel approach called expression selection to precisely define the hepatitis B virus (HBV) enhancer. Expression… 
Highly Cited
1984
Highly Cited
1984
Cloning of the bluetongue virus L3 gene
The genes of the bluetongue virus (BTV) serotype 17 have been cloned into pBR322 by tailing both strands of the double-stranded… 
Highly Cited
1979
Highly Cited
1979
Genes and mRNAs coding for zein polypeptides in Zea mays.
Zein messenger RNAs from maize endosperm were purified by successive oligo(dT)-cellulose chromatography and sucrose gradient… 
Highly Cited
1977
Highly Cited
1977
Multihormonal induction of hepatic alpha2u-globulin mRNA as measured by hybridization to complementary DNA.
A procedure is presented for the preparation of a (3)H-labeled complementary DNA (cDNA) specific for the mRNA coding for alpha(2u… 
Highly Cited
1976
Highly Cited
1976
Radiation leukemia in C57BL/6 mice. II. Lack of ecotropic virus expression in the majority of lymphomas
The expression of endogenous ecotropic viruses in radiation-induced thymomas of C57BL/6 mice was examined. Competition… 
Review
1975
Review
1975
Isolation of infectious C-type oncornavirus from human leukaemic bone marrow cells
C-TYPE ONCORNAVIRUSES are associated with neoplasms of the haemopoietic organs in several vertebrate species1. Molecular…