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RNA-Directed DNA Polymerase
Known as:
RNA Transcriptase
, Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)
, DNA Polymerase, RNA Directed
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An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49…
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National Institutes of Health
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Related topics
Related topics
30 relations
Broader (2)
DNA Nucleotidyltransferases
nucleotidyltransferase
DNA-Directed RNA Polymerase
Enzyme Gene
Gene Products, pol
HIV nonnucleoside reverse transcriptase gene mutations detected:Prid:Pt:Isolate:Nom
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Narrower (6)
LtrA protein, Lactococcus lactis
aI1 endonuclease
aI2 protein, S cerevisiae
maturase I-AniI
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.
G. Grasselli
,
A. Zangrillo
,
+18 authors
A. Pesenti
Journal of the American Medical Association (JAMA…
2020
Corpus ID: 214811452
Importance In December 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) emerged in China…
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Highly Cited
2020
Highly Cited
2020
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study
K. To
,
O. Tsang
,
+22 authors
K. Yuen
Lancet. Infectious Diseases (Print)
2020
Corpus ID: 214679791
Highly Cited
2019
Highly Cited
2019
Search-and-replace genome editing without double-strand breaks or donor DNA
Andrew V. Anzalone
,
Peyton B. Randolph
,
+8 authors
David R. Liu
Nature
2019
Corpus ID: 204832721
Most genetic variants that contribute to disease1 are challenging to correct efficiently and without excess byproducts2–5. Here…
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Highly Cited
2010
Highly Cited
2010
Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
Q. Abdool Karim
,
S. A. Abdool Karim
,
+13 authors
Douglas J. Taylor
Science
2010
Corpus ID: 6079353
Vaginal Gel Versus HIV HIV prevention technologies for women are urgently needed, especially in sub-Saharan Africa where young…
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Highly Cited
2009
Highly Cited
2009
Supervised risk predictor of breast cancer based on intrinsic subtypes.
J. Parker
,
Michael Mullins
,
+17 authors
P. Bernard
Journal of Clinical Oncology
2009
Corpus ID: 27583168
UNLABELLED PURPOSE To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by…
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Review
2002
Review
2002
The biochemistry and medical significance of the flavonoids.
B. Havsteen
Pharmacology and Therapeutics
2002
Corpus ID: 6990440
Highly Cited
1996
Highly Cited
1996
A novel method for real time quantitative RT-PCR.
U E Gibson
,
C. Heid
,
P. M. Williams
Genome Research
1996
Corpus ID: 34517375
A novel approach to quantitative reverse transcriptase polymerase chain reaction (QC RT-PCR) using real time detection and the 5…
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Review
1991
Review
1991
Structure and function of telomeres
E. Blackburn
Nature
1991
Corpus ID: 40486772
The DNA of telomeres—the terminal DNA-protein complexes of chromosomes—differs notably from other DNA sequences in both structure…
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Highly Cited
1985
Highly Cited
1985
Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses.
D. Lane
,
B. Pace
,
G. Olsen
,
D. Stahl
,
M. Sogin
,
N. Pace
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 26883305
Although the applicability of small subunit ribosomal RNA (16S rRNA) sequences for bacterial classification is now well accepted…
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Highly Cited
1980
Highly Cited
1980
Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
B. Poiesz
,
F. Ruscetti
,
A. Gazdar
,
P. Bunn
,
J. Minna
,
R. Gallo
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 34638263
Retrovirus particles with type C morphology were found in two T-cell lymphoblastoid cell lines, HUT 102 and CTCL-3, and in fresh…
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