RBBP8 wt Allele

Known as: COM1, CTIP, JWDS 
Human RBBP8 wild-type allele is located in the vicinity of 18q11.2 and is approximately 93 kb in length. This allele, which encodes retinoblastoma… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics… (More)
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Highly Cited
2010
Highly Cited
2010
The repair of DNA double-strand breaks (DSBs) by homologous recombination is essential for genomic stability. The first step in… (More)
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Highly Cited
2008
Highly Cited
2008
DNA ends exposed after introduction of double-strand breaks (DSBs) undergo 5′–3′ nucleolytic degradation to generate single… (More)
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Highly Cited
2007
Highly Cited
2007
Mre11/Rad50 complexes in all organisms function in the repair of DNA double-strand breaks. In budding yeast, genetic evidence… (More)
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2006
2006
Double-strand breaks (DSBs) elicit a DNA damage response, resulting in checkpoint-mediated cell-cycle delay and DNA repair. The… (More)
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Highly Cited
2005
Highly Cited
2005
When eukaryotic chromosomes undergo double strand breaks (DSBs), several evolutionarily conserved proteins, among which the MRX… (More)
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2004
2004
DNA damage checkpoint pathways sense DNA lesions and transduce the signals into appropriate biological responses, including cell… (More)
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Highly Cited
2002
Highly Cited
2002
Inverted repeats (IRs) that can form a hairpin or cruciform structure are common in the human genome and may be sources of… (More)
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Highly Cited
1997
Highly Cited
1997
We have designed a screen to isolate mutants defective during a specific part of meiotic prophase I of the yeast Saccharomyces… (More)
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1995
1995
During meiosis in Saccharomyces cerevisiae, the first chemical step in homologous recombination is the occurrence of site… (More)
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