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RBBP8 wt Allele

Known as: COM1, CTIP, JWDS 
Human RBBP8 wild-type allele is located in the vicinity of 18q11.2 and is approximately 93 kb in length. This allele, which encodes retinoblastoma… Expand
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
The Mre11-Rad50-Xrs2 nuclease complex, together with Sae2, initiates the 5′-to-3′ resection of Double-Strand DNA Breaks (DSBs… Expand
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Highly Cited
2012
Highly Cited
2012
Several homology-dependent pathways can repair potentially lethal DNA double-strand breaks (DSBs). The first step common to all… Expand
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Highly Cited
2011
Highly Cited
2011
Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics… Expand
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Highly Cited
2008
Highly Cited
2008
DNA ends exposed after introduction of double-strand breaks (DSBs) undergo 5′–3′ nucleolytic degradation to generate single… Expand
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Highly Cited
2007
Highly Cited
2007
Mre11/Rad50 complexes in all organisms function in the repair of DNA double-strand breaks. In budding yeast, genetic evidence… Expand
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Highly Cited
2006
Highly Cited
2006
Double‐strand breaks (DSBs) elicit a DNA damage response, resulting in checkpoint‐mediated cell‐cycle delay and DNA repair. The… Expand
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Highly Cited
2005
Highly Cited
2005
When eukaryotic chromosomes undergo double strand breaks (DSBs), several evolutionarily conserved proteins, among which the MRX… Expand
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Highly Cited
2002
Highly Cited
2002
Inverted repeats (IRs) that can form a hairpin or cruciform structure are common in the human genome and may be sources of… Expand
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Highly Cited
1997
Highly Cited
1997
We have designed a screen to isolate mutants defective during a specific part of meiotic prophase I of the yeast Saccharomyces… Expand
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Highly Cited
1997
Highly Cited
1997
We describe a general new approach for identifying recessive mutations that affect diploid strains of yeast Saccharomyces… Expand
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