RBBP8 protein, human

Known as: CtBP-Interacting Protein, Sporulation in the Absence of SPO11 Protein 2 Homolog, retinoblastoma binding protein 8, human 
Retinoblastoma binding protein 8 (897 aa, ~102 kDa) is encoded by the human RBBP8 gene. This protein is involved in cell cycle checkpoint control.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
05101519922017

Papers overview

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Highly Cited
2011
Highly Cited
2011
DNA non-homologous end joining (NHEJ) and homologous recombination (HR) function to repair DNA double-strand breaks (DSBs) in G2… (More)
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Highly Cited
2011
Highly Cited
2011
Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics… (More)
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Highly Cited
2008
Highly Cited
2008
Characterizing the functional overlap and mutagenic potential of different pathways of chromosomal double-strand break (DSB… (More)
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Highly Cited
2008
Highly Cited
2008
BRCA1 plays an important role in the homologous recombination (HR)-mediated DNA double-strand break (DSB) repair, but the… (More)
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Highly Cited
2007
Highly Cited
2007
In the S and G2 phases of the cell cycle, DNA double-strand breaks (DSBs) are processed into single-stranded DNA, triggering ATR… (More)
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Highly Cited
2007
Highly Cited
2007
The Mre11-Rad50-Nbs1 (MRN) complex is a primary sensor of DNA double-strand breaks (DSBs). Upon recruitment to DSBs, it plays a… (More)
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Highly Cited
2007
Highly Cited
2007
The product of the breast cancer-1 gene, BRCA1, plays a crucial part in the DNA damage response through its interactions with… (More)
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Highly Cited
2004
Highly Cited
2004
The BRCA1 C-terminal (BRCT) domain has recently been implicated as a phospho-protein binding domain. We demonstrate here that a… (More)
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Highly Cited
2000
Highly Cited
2000
BRCA1 encodes a familial breast cancer suppressor that has a critical role in cellular responses to DNA damage. Mouse cells… (More)
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Highly Cited
1998
Highly Cited
1998
The BRCA1 tumor suppressor encodes a polypeptide with two recognizable protein motifs: a RING domain near the N terminus and two… (More)
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