Skip to search formSkip to main contentSkip to account menu

RBBP8 protein, human

Known as: CtBP-Interacting Protein, Sporulation in the Absence of SPO11 Protein 2 Homolog, retinoblastoma binding protein 8, human 
Retinoblastoma binding protein 8 (897 aa, ~102 kDa) is encoded by the human RBBP8 gene. This protein is involved in cell cycle checkpoint control.
National Institutes of Health

Related topics

Related topics

17 relations

Broader (3)

Carrier ProteinsEsterasesNuclear Proteins
Cell Cycle CheckpointsCell Cycle ControlDNA RepairDNA Repair Endonuclease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Ctp1 protein–DNA filaments promote DNA bridging and DNA double-strand break repair
The Ctp1 protein in Schizosaccharomyces pombe is essential for DNA double-strand break (DSB) repair by homologous recombination… 
2016
2016
Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair
Several classes of inhibitors of the mammalian target of rapamycin (mTOR) have been developed based on its central role in… 
2014
2014
miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP
MicroRNA-19 (miR-19) was recently identified as the key oncogenic component of the polycistronic miR-17∼92 cluster, also known as… 
2014
2014
Fork reversal, too much of a good thing
Human cells must faithfully duplicate billions of base pairs of DNA every cell division cycle. Insufficient precursors, DNA… 
2012
2012
Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks
The resection of DNA double-strand breaks (DSBs) into 3′ single-strand tails is the initiating step of homology-dependent repair… 
2009
2009
Cell cycle-dependent processing of DNA lesions controls localization of Rad9 to sites of genotoxic stress
The Rad9/Rad1/Hus1 complex functions to facilitate the ATR-mediated phosphorylation of several substrates that control the… 
Highly Cited
2008
Highly Cited
2008
Molecular Characterization of the Role of the Schizosaccharomyces pombe nip1+/ctp1+ Gene in DNA Double-Strand Break Repair in Association with the Mre11-Rad50-Nbs1 Complex
ABSTRACT The Schizosaccharomyces pombe nip1+/ctp1+ gene was previously identified as an slr (synthetically lethal with rad2… 
2007
2007
Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design.
Protein−protein interactions mediated by the carboxy terminus domains of breast cancer gene 1 (BRCT) play a critical role in the… 
Highly Cited
2004
Highly Cited
2004
Dimerization of CtIP, a BRCA1- and CtBP-interacting Protein, Is Mediated by an N-terminal Coiled-coil Motif*
CtIP is a transcriptional co-regulator that binds a number of proteins involved in cell cycle control and cell development, such… 
2001
2001
Tumour suppressors (Communication arising): Effect of DNA damage on a BRCA1 complex
The tumour-suppressor protein BRCA1 mediates its biological functions by interacting with cellular factors such as the CtIP… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)