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RBBP8 protein, human

Known as: CtBP-Interacting Protein, Sporulation in the Absence of SPO11 Protein 2 Homolog, retinoblastoma binding protein 8, human 
Retinoblastoma binding protein 8 (897 aa, ~102 kDa) is encoded by the human RBBP8 gene. This protein is involved in cell cycle checkpoint control.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
In vertebrate cells, the DNA damage response is controlled by three related kinases: ATM, ATR, and DNA-PK. It has been 20 years… Expand
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Highly Cited
2015
Highly Cited
2015
Error-free repair of DNA double-strand breaks (DSBs) is achieved by homologous recombination (HR), and BRCA1 is an important… Expand
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Highly Cited
2013
Highly Cited
2013
The choice between double-strand break (DSB) repair by either homology-directed repair (HDR) or nonhomologous end joining (NHEJ… Expand
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Highly Cited
2013
Highly Cited
2013
The DNA damage response kinase ataxia telangiectasia and Rad3-related (ATR) coordinates much of the cellular response to… Expand
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Highly Cited
2011
Highly Cited
2011
DNA non-homologous end joining (NHEJ) and homologous recombination (HR) function to repair DNA double-strand breaks (DSBs) in G2… Expand
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Highly Cited
2009
Highly Cited
2009
The Mre11/Rad50/Nbs1 protein complex plays central enzymatic and signaling roles in the DNA-damage response. Nuclease (Mre11) and… Expand
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Highly Cited
2009
Highly Cited
2009
In response to DNA double-strand breaks (DSBs), cells sense the DNA lesions and then activate the protein kinase ATM. Subsequent… Expand
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Highly Cited
2009
Highly Cited
2009
In G(0) and G(1), DNA double strand breaks are repaired by nonhomologous end joining, whereas in S and G(2), they are also… Expand
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Highly Cited
2007
Highly Cited
2007
In the S and G2 phases of the cell cycle, DNA double-strand breaks (DSBs) are processed into single-stranded DNA, triggering ATR… Expand
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Highly Cited
2003
Highly Cited
2003
BRCA1 is a central component of the DNA damage response mechanism and defects in BRCA1 confer sensitivity to a broad range of DNA… Expand
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