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Background: Thrombin and RhoA are linked to cancer cell proliferation. Results: Thrombin induces sustained RhoA-mediated Rap1… Expand Junctional adhesion molecule-A (JAM-A) is a transmembrane tight junction protein that has been shown to regulate barrier function… Expand Summary: Guanine nucleotide binding proteins rapidly cycle between a guanosine diphosphate (GDP)‐bound and guanosine… Expand The AF-6 protein is a multidomain protein that contains two potential Ras-binding domains within its N terminus. Because of this… Expand cAMP (3',5' cyclic adenosine monophosphate) is a second messenger that in eukaryotic cells induces physiological responses… Expand Ras proteins, key regulators of growth, differentiation, and malignant transformation, recently have been implicated in synaptic… Expand The interactions of H-Ras, R-Ras, and Rap1A with the Ras-binding domains (RBD) of the c-Raf kinase and of the Ral guanine… Expand Rap1A is a GTP-binding protein of the Ras superfamily that is highly abundant in phagocyte membranes. Although Rap1A copurifies… Expand Rap1A is a low molecular weight guanosine triphosphate (GTP)-binding protein in human neutrophil membranes whose cellular… Expand Krev-1 is known to suppress transformation by ras. However, the mechanism of the suppression is unclear. The protein product of… Expand