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RAP1A gene

Known as: RAP1A, Member of RAS Oncogene Family Gene, RAS-RELATED PROTEIN 1A, RAP1A, member of RAS oncogene family 
This gene plays a role in signal transduction and cell adhesion.
National Institutes of Health

Related topics

Related topics

5 relations
Homo sapiensRAP1A protein, humanRAP2C geneSignal Transduction

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RAP1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma
Abstract Mitofusin-2 (MFN2) is a mitochondrial protein associated with mitochondrial fusion process. It was initially identified… 
Highly Cited
2008
Highly Cited
2008
The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions.
Highly Cited
2002
Highly Cited
2002
Role of cAMP, PKA and Rap1A in thyroid follicular cell survival
Cyclic AMP (cAMP) rescues cells from apoptosis stimulated by diverse insults. We examined the role of cAMP as a survival factor… 
Highly Cited
1996
Highly Cited
1996
Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
Controlling the hydrolysis rate of GTP bound to guanine nucleotide binding proteins is crucial for the right timing of many… 
Highly Cited
1992
Highly Cited
1992
Subcellular distribution of the Rap1A protein in human neutrophils: colocalization and cotranslocation with cytochrome b559.
Rap1A, a low molecular weight guanosine triphosphate-binding protein (LMWG), has been shown previously by us to be associated… 
1992
1992
Asparagine 26, glutamic acid 31, valine 45, and tyrosine 64 of Ras proteins are required for their oncogenicity.
1992
1992
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells.
Specific antibodies against rap1A and rap1B small GTP-binding proteins were generated by immunization of rabbits with peptides… 
Highly Cited
1991
Highly Cited
1991
The residues of Ras and Rap proteins that determine their GAP specificities.
1991
1991
Heterogeneous amino acids in Ras and Rap1A specifying sensitivity to GAP proteins.
Guanosine triphosphatase (GTPase) activity of Ras is increased by interaction with Ras-GAP (GTPase-activating protein) or with… 
1990
1990
Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins
Normal human rap1A and 35A rap1A (which encodes a protein with a Thr-35----Ala mutation) were cloned into a baculovirus transfer… 
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