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RAP1A gene

Known as: RAP1A, Member of RAS Oncogene Family Gene, RAS-RELATED PROTEIN 1A, RAP1A, member of RAS oncogene family 
This gene plays a role in signal transduction and cell adhesion.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Junctional adhesion molecule-A (JAM-A) is a transmembrane tight junction protein that has been shown to regulate barrier function… Expand
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Highly Cited
2004
Highly Cited
2004
The small GTPase Rap is best characterized as a critical regulator of integrin-mediated cell adhesion, although its mechanism of… Expand
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Highly Cited
2002
Highly Cited
2002
T cell receptor (TCR) stimulation activates the small GTPase Rap1A, which is reported to antagonize Ras signaling and induces T… Expand
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Highly Cited
1999
Highly Cited
1999
Cavernous angiomas are vascular malformations mostly located in the central nervous system and characterized by enlarged… Expand
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Highly Cited
1999
Highly Cited
1999
The Eph family of receptor tyrosine kinases has been implicated in many developmental patterning processes, including cell… Expand
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Highly Cited
1999
Highly Cited
1999
A yeast two-hybrid screening for Ras-binding proteins in nematode Caenorhabditis elegans has identified a guanine nucleotide… Expand
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Highly Cited
1997
Highly Cited
1997
Krev-1/rap1A is an evolutionarily conserved Ras-family GTPase whose cellular function remains unclear, but which has been… Expand
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Highly Cited
1997
Highly Cited
1997
Raf-1 is a major downstream effector of mammalian Ras. Binding of the effector domain of Ras to the Ras-binding domain of Raf-1… Expand
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Highly Cited
1996
Highly Cited
1996
The interactions of H-Ras, R-Ras, and Rap1A with the Ras-binding domains (RBD) of the c-Raf kinase and of the Ral guanine… Expand
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Highly Cited
1994
Highly Cited
1994
Among the small GTPases of the Ras family, Rap proteins exhibit the highest homology with p21Ras. The four Rap proteins so far… Expand
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