Pyrimidine Dimers

Known as: Cyclobutane-Pyrimidine Dimers, Cyclobutane Pyrimidine Dimers, Dimers, Cyclobutane-Pyrimidine 
Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Solar UV radiation is the most important environmental factor involved in the pathogenesis of skin cancers. The well known… (More)
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Highly Cited
2005
Highly Cited
2005
Photolyase transgenic mice have opened new avenues to improve our understanding of the cytotoxic effects of ultraviolet (UV… (More)
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Highly Cited
2003
Highly Cited
2003
The initial step in mammalian nucleotide excision repair (NER) of the major UV-induced photoproducts, cyclobutane pyrimidine… (More)
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Highly Cited
1997
Highly Cited
1997
The most prevalent DNA lesion induced by UV irradiation is the cyclobutane pyrimidine dimer (CPD), which forms at positions of… (More)
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Highly Cited
1994
Highly Cited
1994
Ultraviolet light has been linked with the development of human skin cancers. Such cancers often exhibit mutations in the p53… (More)
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Highly Cited
1992
Highly Cited
1992
Exposing the skin of mice to UV radiation interferes with the induction of delayed and contact hypersensitivity immune responses… (More)
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Highly Cited
1991
Highly Cited
1991
Removal of cyclobutane pyrimidine dimers (CBPDs) in vivo from the DNA of UV-irradiated eight-leaf seedlings of Arabidopsis… (More)
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Highly Cited
1985
Highly Cited
1985
DNA repair was measured in the dihydrofolate reductase gene in Chinese hamster ovary cells, amplified for the gene, by… (More)
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Highly Cited
1984
Highly Cited
1984
Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or… (More)
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Highly Cited
1974
Highly Cited
1974
We have investigated whether mammalian cells can repair pyrimidine dimers in their mitochondrial DNA which have been induced by… (More)
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