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pyrimidine-pyrimidone dimer

Known as: P-PO dimer, pyrimidine-pyrimidone photoproduct, pyrimidine (6-4) pyrimidinone dimer 
National Institutes of Health

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Pyrimidine Dimers

Papers overview

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Review
2016
Review
2016
Chronic Inflammation in Skin Malignancies
Chronic inflammation is linked to the development and progression of multiple cancers, including those of the lung, stomach… 
Review
2013
Review
2013
The variety of UV-induced pyrimidine dimeric photoproducts in DNA as shown by chromatographic quantification methods
Induction of DNA damage is one of the major consequences of exposure to solar UV radiation in living organisms. UV-induced DNA… 
Highly Cited
2008
Highly Cited
2008
Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin.
Highly Cited
2007
Highly Cited
2007
Biomimetic design of reversibly unfolding cross-linker to enhance mechanical properties of 3D network polymers.
We report here a biomimetic design of a reversibly unfolding modular cross-linker to enhance mechanical properties of 3D network… 
Highly Cited
2003
Highly Cited
2003
The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A2.
2001
2001
Stereocontrolled syntheses of carbocyclic C-nucleosides and related compounds.
Carbocyclic 9-deazapurine nucleosides (1-4), a spiranic pyrimidone carbocyclic compound (5), and an unusual carbocyclic… 
Highly Cited
2000
Highly Cited
2000
Replication protein A interactions with DNA. III. Molecular basis of recognition of damaged DNA.
Human replication protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein (subunits of 70, 32, and 14 kDa) that… 
Highly Cited
1998
Highly Cited
1998
The (6-4) photoproduct of thymine-thymine induces targeted substitution mutations in mammalian cells.
Two major ultraviolet-induced photolesions of TpT, a (6-4) photoproduct [T(6-4)T] and a cis-syn cyclobutane TT dimer (T=T), were… 
Highly Cited
1995
Highly Cited
1995
Transcription‐coupled repair removes both cyclobutane pyrimidine dimers and 6‐4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C…
We investigated the contribution of the global and the transcription‐coupled nucleotide excision repair pathway to the removal of… 
Highly Cited
1995
Highly Cited
1995
Induction of cyclobutane pyrimidine dimers, pyrimidine(6-4)pyrimidone photoproducts, and Dewar valence isomers by natural sunlight in normal human mononuclear cells.
Immunocytochemistry was used for the direct measurement of cyclobutane pyrimidine dimers, (6-4) photoproducts, and Dewar isomers… 
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