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Protriptyline

Known as: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-Dibenzo[a,D]cyclohepten-5-yl)-N-methyl-1-propanamine, Protriptylinum 
Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (3)

10,11-dihydro-10,11-dihydroxyprotriptylineProtriptyline HydrochlorideVivactil

Broader (3)

Adrenergic Uptake InhibitorsTricyclic Antidepressive Agentscycloheptane
Affective Disorders, PsychoticAntidepressive AgentsDepressive disorderDrug Allergy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Olefins as steering ligands for homogeneously catalyzed hydrogenations.
Iridium(I) complexes containing a (5H-dibenzo[a,d]cyclohepten-5-yl)-phosphane (tropp(R); R = phosphorus-bound substituent = Ph… 
Highly Cited
2003
Highly Cited
2003
Disposable amperometric immunosensor for the detection of polycyclic aromatic hydrocarbons (PAHs) using screen-printed electrodes.
Highly Cited
1996
Highly Cited
1996
Direct evidence for a role of glutamate in the expression of the opioid withdrawal syndrome.
Highly Cited
1995
Highly Cited
1995
Identification and quantitation of dibenzo[a,l]pyrene--DNA adducts formed by rat liver microsomes in vitro: preponderance of depurinating adducts.
Dibenzo[a,l]pyrene (DB[a,l]P) is the most potent carcinogen known among aromatic hydrocarbons. DB[a,l]P-11,12-dihydrodiol… 
Highly Cited
1995
Highly Cited
1995
A Possible Role of Glutathione as an Endogenous Agonist at the N‐Methyl‐d‐Aspartate Recognition Domain in Rat Brain
Abstract: Glutathione, both reduced (GSH) and oxidized (GSSG), was effective in displacing binding of l‐[3H]‐glutamic acid (l‐[3H… 
Highly Cited
1990
Highly Cited
1990
Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-methyl-D-aspartate antagonists.
A series of 73 dibenzo[a,d]cycloalkenimines were synthesized and evaluated for their ability to displace (+)-10,11-dihydro-5… 
Highly Cited
1989
Highly Cited
1989
Tumor-initiating activity in mouse skin and carcinogenicity in rat mammary gland of dibenzo[a]pyrenes: the very potent environmental carcinogen dibenzo[a, l]pyrene
SummaryComparative studies of tumor-initiating activity in mouse skin and carcinogenicity in rat mammary gland were conducted… 
Highly Cited
1987
Highly Cited
1987
Analgesic properties of intrathecally administered heterocyclic antidepressants
Highly Cited
1978
Highly Cited
1978
Sexual behavior in male rats after intracerebral injection of 5,7-dihydroxytryptamine
Highly Cited
1967
Highly Cited
1967
The effect of beta-phenylethylamine on central and peripheral monoamine-containing neurons.
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