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Protriptyline

Known as: 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine, 3-(5H-Dibenzo[a,D]cyclohepten-5-yl)-N-methyl-1-propanamine, Protriptylinum 
Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (3)

10,11-dihydro-10,11-dihydroxyprotriptylineProtriptyline HydrochlorideVivactil

Broader (3)

Adrenergic Uptake InhibitorsTricyclic Antidepressive Agentscycloheptane
Affective Disorders, PsychoticAntidepressive AgentsDepressive disorderDrug Allergy

Papers overview

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1987
1987
Simultaneous Quantitation of Eight Tricyclic Antidepressants in Serum by High‐Performance Liquid Chromatography
Summary An analytical procedure has been developed for the simultaneous separation and quantitation of amitriptyline (AMI… 
1986
1986
Bethanechol chloride can reverse erectile and ejaculatory dysfunction induced by tricyclic antidepressants and mazindol: case report.
A 43-year-old man who experienced profound dose-related erectile and ejaculatory dysfunction without loss of libido on three… 
1983
1983
Liquid chromatographic separation of antidepressant drugs: I. Tricyclics.
A simple normal-phase (silica), high-performance liquid chromatographic (HPLC) assay of amitriptyline (AMI), doxepin (DOX… 
1979
1979
Dibenzotropone- and dibenzosuberonecarboxylic acids with bronchodilator activity.
The syntheses of 44 5H-dibenzo[a,d]cyclohepten-5-one derivatives bearing a carboxyl gropu at the 1, 2, 3, or 10 position and… 
1978
1978
Analysis of tricyclic antidepressants in human plasma by GLC--chemical-ionization mass spectrometry with selected ion monitoring.
A method is described for the analysis of amitriptyline, doxepin, imipramine, nortriptyline, desmethyldoxepin, desipramine, and… 
1977
1977
Dibenztroponeacetic and -propionic acids. Potent new antiinflammatory agents.
The syntheses and antiinflammatory assays of some dibenztroponeacetic and -propionic acids and derivatives are described. The… 
1976
1976
Isolation of 10, 11-epoxide of protriptyline in rat urine after protriptyline administration.
The 10, 11-epoxide, 10-hydroxy, and 10, 11-dihydrodiol metabolites of protriptyline were identified in rat urine collected after… 
1972
1972
Effect of lithium on the analgesia caused by morphine and two antidepressants in mice.
The effect of lithium on the antinociceptive action of morphine and two tricyclic antidepressants, imipramine and protriptyline… 
1967
1967
Uptake and release of alpha-methyl-noradrenaline in vitro after reserpine pretreatment. A histochemical study.
The reserpine-rcsistent uptake and storage of α-methyl-noradrenaline in vitro were investigated in thr adrenergic nerves of the… 
1963
1963
THE USE OF PROTRYPTYLINE (MK-240) AS AN ANTIDEPRESSANT; A PRELIMINARY REPORT.
1. Protryptyline (MK-240) is an effective antidepressant. 2. Its major usefulness appears to be for patients with retardation and…