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Proto-Oncogene Proteins c-akt

Known as: Related to A and C-Protein, Protein Kinase B, c-akt Protein 
Expressed in diverse tissues, Protein Kinase B (AKT/RAC Family) is a group (Alpha, Beta and Gamma) of cytoplasmic serine/threonine enzymes that… 
National Institutes of Health

Related topics

Related topics

18 relations
7-hydroxystaurosporineAKT1 geneIn BloodProcess of secretion

Narrower (5)

AKT2 protein, humanAKT3 protein, humanRAC-Alpha Serine/Threonine Kinaseprotein kinase B gamma

Papers overview

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2010
2010
Proteasome inhibition leads to dephosphorylation and downregulation of protein expression of members of the Akt/mTOR pathway in MCL
Proteasome inhibition leads to dephosphorylation and downregulation of protein expression of members of the Akt/mTOR pathway in… 
2008
2008
Improved clinical and cell cycle response with an mTOR inhibitor, daily oral RAD001 (everolimus) plus letrozole versus placebo plus letrozole in a randomized phase II neoadjuvant trial in ER+ breast…
530 Background: Activation of the mTOR pathway is a key adaptive change driving endocrine resistance. RAD001, an oral mTOR… 
Highly Cited
2007
Highly Cited
2007
Interchain-solvent-induced chirality change of 1D helical chains: from achiral to chiral crystallization.
Three helical supramolecular stereoisomers of meso-2, Delta-2, and Delta-3 with the formula of cis-[Ni(f-rac-L)][Ni(CN)4] were… 
2006
2006
Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.
EGF suppresses proteolysis via class 1 phosphatidylinositol 3-kinase (PI3K) in renal tubular cells. EGF also increases the… 
Highly Cited
2005
Highly Cited
2005
Insulin-like Growth Factor-1 ( IGF-1 ) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase / Akt / Mammalian Target of Rapamycin ( PI 3 K / Akt / mTOR ) Pathway *
Skeletal muscle size is regulated by anabolic (hypertrophic) and catabolic (atrophic) processes. We first characterized molecular… 
2005
2005
REGULATION OF MDR 1 EXPRESSION AND DRUG RESISTANCE BY A POSITIVE FEEDBACK LOOP INVOLVING HYALURONAN , PHOSPHOINOSITIDE 3-KINASE AND ERBB 2 *
FEEDBACK LOOP INVOLVING HYALURONAN, PHOSPHOINOSITIDE 3-KINASE AND ERBB2* Suniti Misra, Shibnath Ghatak and Bryan P. Toole… 
2000
2000
Advances in Brief Modulation of Hypoxia-inducible Factor 1 a Expression by the Epidermal Growth Factor / Phosphatidylinositol 3-Kinase / PTEN / AKT / FRAP Pathway in Human Prostate Cancer Cells…
Dysregulated signal transduction from receptor tyrosine kinases to phosphatidylinositol 3-kinase (PI3K), AKT (protein kinase B… 
2000
2000
The Phosphatidylinositol 3-Kinase / AKT Kinase Pathway in Multiple Myeloma Plasma Cells : Roles in Cytokine-dependent Survival and Proliferative Responses 1
Interleukin 6 (IL-6) and insulin-like growth factor I (IGF-I) induce proliferative and antiapoptotic responses in multiple… 
1989
1989
Activators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins.
Activation of human T cells through the CD3-T cell receptor complex caused an augmentation in the cell surface expression of CD2… 
Highly Cited
1949
Highly Cited
1949
Über die Entstehung von Mesonen in Vielfachprozessen
ZusammenfassungDie Annahme, daß beim Stoß zweier energiereicher Nukleonen durch eine nichtlineare Wechselwirkung viele Mesonen in…