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AKT2 protein, human

Known as: RAC-Beta Serine/Threonine Kinase, PKBbeta, human, AKT2 
RAC-beta serine/threonine-protein kinase (481 aa, ~56 kDa) is encoded by the human AKT2 gene. This protein is involved in protein phosphorylation… 
National Institutes of Health

Related topics

Related topics

28 relations
AKT2 geneAKT2 wt AlleleAKT3 protein, humanAdipocytokine Signaling Pathway

Broader (3)

Protein-Serine-Threonine KinasesProto-Oncogene Proteins c-aktrac-PK beta

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Regulation of basal expression of hepatic PEPCK and G6Pase by AKT2.
Hepatic glucose metabolism signaling downstream of insulin can diverge to multiple pathways including AKT.  Genetic studies… 
2016
2016
Insulin-induced Effects on the Subcellular Localization of AKT1, AKT2 and AS160 in Rat Skeletal Muscle
AKT1 and AKT2, the AKT isoforms that are highly expressed in skeletal muscle, have distinct and overlapping functions, with AKT2… 
2016
2016
The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node… 
2014
2014
Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules
Aberrant AKT activation is prevalent across multiple human cancer lineages providing an important new target for therapy. Twenty… 
Highly Cited
2012
Highly Cited
2012
Receptor-Specific Mechanisms Regulate Phosphorylation of AKT at Ser473: Role of RICTOR in β1 Integrin-Mediated Cell Survival
A tight control over AKT/PKB activation is essential for cells, and they realise this in part by regulating the phosphorylation… 
2011
2011
The K+ battery-regulating Arabidopsis K+ channel AKT2 is under the control of multiple post-translational steps
Potassium (K+) is an important nutrient for plants. It serves as a cofactor of various enzymes and as the major inorganic solute… 
2009
2009
Strain-induced Proliferation Requires the Phosphatidylinositol 3-Kinase/AKT/Glycogen Synthase Kinase Pathway*
The intestinal epithelium is repetitively deformed by shear, peristalsis, and villous motility. Such repetitive deformation… 
2007
2007
Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors.
Epithelial tumorigenesis has been linked to AKT up-regulation. Human papillomaviruses (HPV) cause anogenital cancers and… 
Highly Cited
2005
Highly Cited
2005
A Unique Voltage Sensor Sensitizes the Potassium Channel AKT2 to Phosphoregulation
Among all voltage-gated K+ channels from the model plant Arabidopsis thaliana, the weakly rectifying K+ channel (Kweak channel… 
Highly Cited
2005
Highly Cited
2005
Inward rectification of the AKT2 channel abolished by voltage-dependent phosphorylation.
The Arabidopsis K(+) channel AKT2 possesses the remarkable property that its voltage threshold for activation can be either… 
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