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AKT3 protein, human

Known as: AKT serine-threonine kinase 3, human, V-Akt Murine Thymoma Viral Oncogene Homolog 3, RAC-Gamma Serine/Threonine Kinase 
RAC-beta serine/threonine-protein kinase (479 aa, ~56 kDa) is encoded by the human AKT3 gene. This protein plays a role in protein phosphorylation… 
National Institutes of Health

Related topics

Related topics

29 relations
AKT2 protein, humanAKT3 geneAdipocytokine Signaling PathwayApoptosis

Broader (3)

Protein-Serine-Threonine KinasesProto-Oncogene Proteins c-aktprotein kinase B gamma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Upregulation of miR-582-5p regulates cell proliferation and apoptosis by targeting AKT3 in human endometrial carcinoma
Highly Cited
2016
Highly Cited
2016
Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4
Background Treatment of breast cancer patients with distant metastases represents one of the biggest challenges in today’s… 
2016
2016
The role of AKT isoforms in glioblastoma: AKT3 delays tumor progression
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node… 
2016
2016
Functional Effects of AKT3 on Aurora Kinase Inhibitor-induced Aneuploidy*
The suppression of mitotic Aurora kinases (AURKs) by AURK inhibitors frequently causes cytokinetic failure, leading to polyploidy… 
2016
2016
AKT3 represses aneuploidy
The suppression of mitotic Aurora kinases (AURKs) by AURK inhibitors frequently causes cytokinetic failure, leading to polyploidy… 
2015
2015
OverAKT3: tumor progression and chemoresistance
Akt3 is one of 3 closely related serine/threonine-protein kinases in the Akt family (Akt1, Akt2, and Akt3). Akt is among the most… 
2014
2014
The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis
The AKT3 signalling pathway plays a critical role in melanoma formation and invasion and components of this signalling cascade… 
2014
2014
AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM‐1
Our previous work has shown that Akt3 is required for mitochondrial biogenesis in primary human endothelial cells (ECs) and in… 
Review
2011
Review
2011
AKT3 (v-akt murine thymoma viral oncogene homolog 3, Protein Kinase B gamma)
Review on AKT3 (v-akt murine thymoma viral oncogene homolog 3, Protein Kinase B gamma), with data on DNA, on the protein encoded… 
1997
1997
Characterization of two different cytoplasmic protein tyrosine kinases from human breast cancer.
Two different protein tyrosine kinases were detected in the cytosolic fraction of different human tumor tissues. After partial… 
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