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AKT2 gene

Known as: PKB-BETA, PKBB, ONCOGENE AKT2 
This gene plays a role in glucose homeostasis and the inhibition of apoptosis.
National Institutes of Health

Related topics

Related topics

11 relations
AKT2 protein, humanAKT2 wt AlleleCarbohydrate MetabolismDiabetes Mellitus, Non-Insulin-Dependent

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
miR‐503 expression is downregulated in cervical cancer and suppresses tumor growth by targeting AKT2
Previous studies have reported that microRNAs function as key regulators in tumor development and progression. This study aims to… 
2019
2019
miR-137 functions as a tumor suppressor gene in pituitary adenoma by targeting AKT2.
Pituitary adenoma is a common intracranial tumor, but the underlying molecular carcinogenesis mechanisms remain unclear… 
2017
2017
miR-148a suppresses human renal cell carcinoma malignancy by targeting AKT2.
MicroRNA-148a (miR-148a) has been reported to be deregulated in different tumor types, whereas the biological function of miR… 
2017
2017
AKT2 deficiency induces retardation of myocyte development through EndoG-MEF2A signaling in mouse heart.
2015
2015
MORFAN Syndrome: An Infantile Hypoinsulinemic Hypoketotic Hypoglycemia Due to an AKT2 Mutation.
2012
2012
Anti‐tumor efficacy of naked siRNAs for ERBB3 or AKT2 against lung adenocarcinoma cell xenografts
The use of siRNAs against specific molecular targets has potential for cancer therapy but has been thought to be limited by the… 
2010
2010
Dual Inhibition of mTORC1/mTORC2 Induces Apoptosis of Mantle Cell Lymphoma by Preventing Rictor Mediated AKTS473 Phosphorylation by Potentiating AKT2-PHLPP1 Association
Abstract 772 The mammalian target of rapamycin (mTOR) plays a crucial role in proliferative and anti-apoptotic signals in various… 
2008
2008
First Evidence of Genetic Association Between AKT2 and Polycystic Ovary Syndrome
OBJECTIVE—Insulin resistance has been reported in up to 70% of women with polycystic ovary syndrome (PCOS). Physiologic and… 
2006
2006
[Expression of AKT2, cyclin D1, and MMP-9 and their correlations to clinicopathologic features of non-small cell lung cancer].
BACKGROUND & OBJECTIVE AKT2, a serine/threonine kinase, is confirmed to be an oncogene. Abnormal expression and activation of… 
1998
1998
Translocation and activation of AKT2 in response to stimulation by insulin
The AKT2 oncogene encodes a protein‐serine/threonine kinase that was recently shown to be activated by a variety of growth… 
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