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Protein Geranylgeranylation

Known as: C-terminal protein geranylgeranylation, Geranylgeranylation, Protein, protein amino acid geranylgeranylation 
OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy terminus of a protein. [GOC:jl]
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

GeranylgeranylationProtein Prenylation

Papers overview

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Highly Cited
2009
Highly Cited
2009
Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27Kip1 Phosphorylation on Thr187 and Accumulates p27Kip1 in the Nucleus: Implications for Breast Cancer Therapy
ABSTRACT We describe the design of a potent and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI), GGTI… 
2009
2009
Immunoisolation of striatal dopaminergic nerve terminals defines susceptibility to MPTP toxicity in C57BL/6 mice
2009
2009
Constitutive dimer formation of TDP-43 in human cell lines
2009
2009
p-Nitrotoluene models of rat Parkinsonism
2009
2009
The spinal anterior horn has the capacity to self-regenerate in ALS model mice
Highly Cited
2007
Highly Cited
2007
SnapShot: Rho Family GTPases
2007
2007
Synthesis of fluorescently tagged isoprenoid bisphosphonates that inhibit protein geranylgeranylation.
2006
2006
Erythropoietin Receptor Signal Transduction Requires Protein Geranylgeranylation
Erythropoietin (Epo) acts through the erythropoietin receptor, a member of the type-1 cytokine receptor family, to influence… 
2005
2005
Geranylgeranylated proteins are involved in the regulation of myeloma cell growth.
PURPOSE Prenylation is essential for membrane localization and participation of proteins in various signaling pathways. This… 
Highly Cited
1999
Highly Cited
1999
Integrin-dependent Leukocyte Adhesion Involves Geranylgeranylated Protein(s)*
Integrin-dependent leukocyte adhesion is modulated by alterations in receptor affinity or by post-receptor events. Pretreatment… 
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