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Geranylgeranylation

 
National Institutes of Health

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2015
2015
PDZ binding-kinase (PBK) (also named T-lymphokine-activated killer cell-originated protein kinase (TOPK)), a serine/threonine… Expand
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2011
2011
Prenylation is a post-translational hydrophobic modification of proteins, important for their membrane localization and… Expand
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2010
2010
Mevalonate kinase deficiency (MKD) is an autoinflammatory disorder caused by mutations in the MVK gene resulting in decreased… Expand
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2007
2007
Bisphosphonates are widely used agents for the treatment of malignant bone disease. They inhibit osteoclast-mediated bone… Expand
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2006
2006
HMG-CoA reductase inhibitors (statins) are widely used in the treatment and prevention of atherosclerosis. Here we demonstrate… Expand
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2005
2005
RhoA plays a critical signaling role in thrombin-induced endothelial dysfunction. The possible thrombin regulation of… Expand
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2005
2005
BackgroundAvailable in vitro and in vivo methods for verifying protein substrates for posttranslational modifications via… Expand
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2004
2004
Inflammatory responses involving microglia, the resident macrophages of the brain, are thought to contribute importantly to the… Expand
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Highly Cited
2001
Highly Cited
2001
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may exert pleiotropic effects on vascular cells independent… Expand
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1990
1990
smg p21A and -B are small GTP-binding proteins that share putative effector and consensus C-terminal sequences with ras p21… Expand
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