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Protein Prenylation

Known as: C-terminal protein prenylation, Prenylation, Protein, protein amino acid prenylation 
A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl… 
National Institutes of Health

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Related topics

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Broader (1)

Prenylation

Narrower (3)

Protein FarnesylationProtein GeranylgeranylationProtein Isoprenylation
aspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Assessment of Protein Prenylation Pathway in Multiple Sclerosis Patients
Multiple sclerosis (MS) is a chronic inflammatory disorder with several genetic and environmental factors being implicated in its… 
2016
2016
Exploration of GGTase-I substrate requirements. Part 2: Synthesis and biochemical analysis of novel saturated geranylgeranyl diphosphate analogs.
2008
2008
Zoledronic acid (ZOMETA): a significant improvement in the treatment of Bone metastases
Bone metastases are frequent complications of breast, lung and prostate cancers, multiplex myeloma, and less frequently of other… 
2008
2008
Post-diagnosis statin use and breast recurrence sites in early stage breast cancer survivors
To the Editor, We read the article by Kwan et al. [1] in which they showed an inverse association between post-diagnosis… 
2006
2006
Role of inhibition of protein prenylation in the cholesterol-dependent and cholesterol-independent effects of simvastatin
2005
2005
The effect of D-003 (10 mg/day) on biochemical parameters of bone remodelling in postmenopausal women: a randomized, double-blind study.
Biphosphonates, which are antiresorptive agents used to treat osteoporosis, inhibit the mevalonate pathway, preventing protein… 
2002
2002
Didehydrogeranylgeranyl (Delta Delta GG): a fluorescent probe for protein prenylation.
The first intrinsically fluorescent analog of geranylgeraniol, (2E,6E,8E,10E,12E,14E)-geranylgeraniol (all-trans-DeltaDeltaGGOH.1… 
Highly Cited
2000
Highly Cited
2000
Induction of apoptosis in malignant B cells by phenylbutyrate or phenylacetate in combination with chemotherapeutic agents.
Phenylacetate (PA) and phenylbutyrate (PB) are aromatic fatty acids that are presently undergoing evaluation as potential… 
2000
2000
Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance
The Rab/Ypt small G proteins are essential for intracellular vesicle trafficking in mammals and yeast. The vesicle‐docking… 
Review
1995
Review
1995
Mechanisms of protein prenylation and role in G protein function.
Introduction Covalent attachment of isoprenoid lipids is now recognized as an important modification of many proteins involved in… 
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