Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Protein Prenylation

Known as: C-terminal protein prenylation, Prenylation, Protein, protein amino acid prenylation 
A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
G protein‐regulated cell function is crucial for cardiomyocytes, and any deregulation of its gene expression or protein… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Statins are cholesterol-lowering drugs that inhibit 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase, the rate-limiting enzyme… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2012
2012
Accumulation of β-amyloid (Aβ) inside brain neurons is an early and crucial event in Alzheimer's disease (AD). Studies in brains… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Protein prenyltransferases catalyze the attachment of C15 (farnesyl) and C20 (geranylgeranyl) groups to proteins at specific… Expand
Is this relevant?
2009
2009
Simvastatin inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which catalyses conversion of HMG-CoA to… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2006
Review
2006
In eukaryotic cells, a specific set of proteins are modified by C-terminal attachment of 15-carbon farnesyl groups or 20-carbon… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Statins such as simvastatin are 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors that inhibit cholesterol synthesis. We… Expand
Is this relevant?
2002
2002
Apolipoprotein E (ApoE) genotype modulates the risk of Alzheimer's disease. ApoE has been shown essential for amyloid beta… Expand
Is this relevant?
2000
2000
Phenylacetate (PA) and phenylbutyrate (PB) are aromatic fatty acids that are presently undergoing evaluation as potential… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Review
1995
Review
1995
  • P. Casey
  • Biochemical Society transactions
  • 1995
  • Corpus ID: 29102829
Introduction Covalent attachment of isoprenoid lipids is now recognized as an important modification of many proteins involved in… Expand
  • figure I
Is this relevant?